CAS 102394-31-0

11-[2-[2-[(Diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one

Description:

The chemical substance known as 11-[2-[2-[(Diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one, with the CAS number 102394-31-0, is a complex organic compound that belongs to the class of benzodiazepines. It features a multi-cyclic structure that includes a pyrido and benzodiazepine moiety, which contributes to its pharmacological properties. The presence of a diethylamino group suggests potential interactions with neurotransmitter systems, particularly in the central nervous system. This compound may exhibit various biological activities, including anxiolytic or sedative effects, typical of benzodiazepines, although specific pharmacological data would be necessary to confirm its efficacy and safety profile. Its intricate structure indicates that it may undergo various metabolic pathways, influencing its bioavailability and half-life. As with many compounds in this class, careful consideration of its chemical properties, such as solubility, stability, and reactivity, is essential for its application in medicinal chemistry and drug development.

Formula: C₂₄H₃₁N₅O₂

InChI: InChI=1S/C24H31N5O2/c1-3-27(4-2)16-18-10-7-8-15-28(18)17-22(30)29-21-13-6-5-11-19(21)24(31)26-20-12-9-14-25-23(20)29/h5-6,9,11-14,18H,3-4,7-8,10,15-17H2,1-2H3,(H,26,31)

InChI key: InChIKey=UBRKDAVQCKZSPO-UHFFFAOYSA-N

SMILES: C(CN1C(CN(CC)CC)CCCC1)(=O)N2C=3C(C(=O)NC=4C2=NC=CC4)=CC=CC3

Synonyms:

• 11-((2-((Diethylamino)methyl)-1-piperidinyl)acetyl)-5,11-dihydro-(6H)-pyrido[2.3-b][1.4]benzodiazepin-6-one
• 11-[2-[2-(Diethylaminomethyl)piperidin-1-yl]acetyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one
• 11-[2-[2-[(Diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
• 6H-Pyrido(2,3-B)(1,4)Benzodiazepin-6-One,5,11-Dihydro-11-((2-((Diethylamino)M
• 6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one, 11-[2-[2-[(diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-
• 6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one, 11-[[2-[(diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-
• Af-Dx 116
• Ethyl)-7-Piperidinyl)Acetyl)-
• Otenzepad

6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one, 11-[2-[2-[(diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-

CAS: 102394-31-0

Formula: C₂₄H₃₁N₅O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 421.5352

Ref: IN-DA0007BO

Otenzepad

CAS: 102394-31-0

Otenzepad

Purity: ≥98%

Molecular weight: 421.54g/mol

Ref: 54-BUP05581

AF-DX 116

Controlled Product

CAS: 102394-31-0

Formula: C₂₄H₃₁N₅O₂

Color and Shape: Neat

Molecular weight: 421.535

Ref: TR-A355358

Otenzepad

CAS: 102394-31-0

Otenzepad is a fluorescent probe that can bind to muscarinic receptors and be used as a research tool. It is an antagonist of the muscarinic receptor, which inhibits the neurotransmitter acetylcholine from binding to the receptor. Otenzepad has low potency and is not selective for any one type of muscarinic receptor, but it does have high affinity for all types. Otenzepad binds to cholinergic neurons by competitive inhibition, preventing acetylcholine from binding to the receptor and inhibiting their function. This results in decreased production of other chemicals that are important for memory and learning processes. Atropine and pirenzepine are muscarinic antagonists that are used in medical practice as anticholinergics or antispasmodics. They block acetylcholine receptors on smooth muscle cells, leading to increased bladder contraction and reduced gastrointestinal motility. Estrogen-benzoate also has antagonistic effects on the muscarinic

Formula: C₂₄H₃₁N₅O₂

Purity: Min. 95%

Molecular weight: 421.54 g/mol

Ref: 3D-CEA39431

Otenzepad

CAS: 102394-31-0

Otenzepad (AF-DX 116) is a selective antagonist of M2 mAChR with IC50s of 386 nM and 640 nM for rat heart and rabbit peripheral lung.

Formula: C₂₄H₃₁N₅O₂

Purity: 99.79%

Color and Shape: Solid

Molecular weight: 421.54

Ref: TM-T16411