CAS 1024-99-3

5-Iodouridine

Description:

5-Iodouridine is a nucleoside analog characterized by the presence of an iodine atom at the 5-position of the uridine molecule. This modification can influence its biological activity, particularly in the context of antiviral and anticancer research. The compound retains the basic structure of uridine, which consists of a ribose sugar linked to a uracil base, but the iodine substitution can enhance its interaction with nucleic acid targets. 5-Iodouridine is often studied for its potential to inhibit viral replication and its role in various biochemical pathways. Its solubility and stability in biological systems can vary, affecting its pharmacokinetics and bioavailability. Additionally, the presence of iodine may impart unique spectroscopic properties, making it useful in certain analytical techniques. Overall, 5-Iodouridine serves as an important tool in medicinal chemistry and molecular biology, providing insights into nucleoside function and the development of therapeutic agents.

Formula: C₉H₁₁IN₂O₆

InChI: InChI=1S/C9H11IN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1

InChI key: InChIKey=RKSLVDIXBGWPIS-UAKXSSHOSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(I)=C2

Synonyms:

• 5-Iodo-Uridine
• 5-iodo-1-pentofuranosylpyrimidine-2,4(1H,3H)-dione
• Nsc 523375
• Uridine, 5-iodo-
• Uridine, 5-iodo- (8CI)(9CI)
• 5-Iodouridine

5-Iodouridine

CAS: 1024-99-3

Formula: C₉H₁₁IN₂O₆

Purity: >97.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 370.10

Ref: 3B-I1154

5-Iodouridine

CAS: 1024-99-3

Formula: C₉H₁₁IN₂O₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 370.099

Ref: 10-F213700

5-Iodouridine, 96%

CAS: 1024-99-3

5-Iodouridine has shown to enhance the effect of gamma irradiation in hamster cells. It is used as catalytic agent, petrochemical additive, used in organic synthesis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label

Formula: C₉H₁₁IN₂O₆

Purity: 96%

Molecular weight: 370.1

Ref: 02-J62259

Uridine, 5-iodo-

CAS: 1024-99-3

Formula: C₉H₁₁IN₂O₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 370.0979

Ref: IN-DA0007DA

5-Iodouridine

CAS: 1024-99-3

5-Iodouridine

Purity: 98%

Molecular weight: 370.10g/mol

Ref: 54-OR1011892

5-Iodouridine

CAS: 1024-99-3

Formula: C₉H₁₁IN₂O₆

Molecular weight: 370.10

Ref: 7W-GE3314

5-Iodouridine

CAS: 1024-99-3

Nucleoside, halo-nucleoside

Formula: C₉H₁₁IN₂O₆

Color and Shape: Solid

Molecular weight: 370.1

Ref: TM-TNU0620

5-Iodouridine

CAS: 1024-99-3

5-Iodouridine is a pyrimidine nucleoside that is found in the human body. It is used as a starting material for the synthesis of 5-iodo-2'-deoxyuridine, which has been shown to have biological properties. 5-Iodouridine binds to the dna template and prevents radiation from altering it's conformation. This binding has been shown to be specific for ultraviolet (UV) radiation, with little absorption at visible wavelengths. The biological effects of 5-iodouridine are dependent on its acidic pH and hydrogen bonding ability. In vitro assays have demonstrated that this compound can inhibit prostate cancer cells from proliferating and may be useful in treating cervical cancer.

Formula: C₉H₁₁IN₂O₆

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 370.1 g/mol

Ref: 3D-NI02225