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CAS 102410-65-1

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Fmoc-L-alpha-phenylglycine

Description:
Fmoc-L-alpha-phenylglycine is a derivative of phenylglycine, commonly used in peptide synthesis and as a building block in organic chemistry. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino functionality, allowing for selective reactions without interfering with the amine. This compound typically appears as a white to off-white solid and is soluble in organic solvents such as dichloromethane and dimethylformamide, but is less soluble in water. Its structure features a phenyl group attached to the alpha carbon of glycine, contributing to its hydrophobic characteristics. Fmoc-L-alpha-phenylglycine is valued for its ability to enhance the stability and solubility of peptides during synthesis. Additionally, it is utilized in various applications, including drug development and the study of protein interactions. Safety data should be consulted, as with all chemical substances, to ensure proper handling and usage in laboratory settings.
Formula:C23H19NO4
InChI:InChI=1/C23H19NO4/c25-22(26)13-15-6-5-7-16(12-15)24-23(27)28-14-21-19-10-3-1-8-17(19)18-9-2-4-11-20(18)21/h1-12,21H,13-14H2,(H,24,27)(H,25,26)
SMILES:c1ccc2c(c1)c1ccccc1C2COC(=Nc1cccc(c1)CC(=O)O)O
Synonyms:
  • Fmoc-L-phenylglycine
  • Fmoc-Phg-OH
  • (2R)-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}(phenyl)ethanoic acid
  • (2S)-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}(phenyl)ethanoic acid
  • (3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}phenyl)acetic acid
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