CAS 1024583-85-4

N-[3-[3-(2-Amino-2-oxoethyl)-1H-indol-1-yl]propyl]-carbamic Acid 1,1-Dimethylethyl Ester

Controlled Product

CAS: 1024583-85-4

Applications N-​[3-​[3-​(2-​Amino-​2-​oxoethyl)​-​1H-​indol-​1-​yl]​propyl]​-​carbamic Acid 1,​1-​Dimethylethyl Ester is an intermediate in synthesizing Bisindolylmaleimide III Hydrochloride (B448480), a protein kinase C inhibitor and was also shown to exhibit inhibitory activities towards PDK1, an important kinase in the insulin signaling pathway.
References Jena, N.R., et al.: J. Molec. Model., 18, 631 (2012); Murphy, R.C., et al.: ACS. Med. Chem. Lett., 1, 331 (2010)

Formula: C₁₈H₂₅N₃O₃

Color and Shape: Neat

Molecular weight: 331.41

Ref: TR-A616315