CAS 102507-71-1

Tigemonam

Description:

Tigemonam is a synthetic antibiotic belonging to the class of beta-lactam antibiotics, specifically a monobactam. It is characterized by its broad-spectrum activity against various Gram-negative bacteria, making it a valuable option in treating infections caused by these pathogens. Tigemonam works by inhibiting bacterial cell wall synthesis, which ultimately leads to cell lysis and death. Its unique structure allows it to evade some common beta-lactamases produced by bacteria, enhancing its efficacy against resistant strains. Tigemonam is typically administered via injection and has been studied for its pharmacokinetics, showing good distribution in body tissues. While it is effective against a range of infections, its use may be limited due to potential side effects and the emergence of bacterial resistance. As with other antibiotics, it is crucial to use Tigemonam judiciously to preserve its effectiveness and minimize the development of resistance. Overall, Tigemonam represents an important tool in the antibiotic arsenal, particularly for treating serious infections caused by resistant Gram-negative bacteria.

Formula: C₁₂H₁₅N₅O₉S₂

InChI: InChI=1/C12H15N5O9S2/c1-12(2)8(10(21)17(12)26-28(22,23)24)15-9(20)7(16-25-3-6(18)19)5-4-27-11(13)14-5/h4,8H,3H2,1-2H3,(H2,13,14)(H,15,20)(H,18,19)(H,22,23,24)/b16-7-/t8-/m1/s1

InChI key: InChIKey=VAMSVIZLXJOLHZ-QWFSEIHXSA-N

SMILES: N(C(/C(=N\OCC(O)=O)/C=1N=C(N)SC1)=O)[C@H]2C(C)(C)N(OS(=O)(=O)O)C2=O

Synonyms:

• ({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-{[(3S)-2,2-dimethyl-4-oxo-1-(sulfooxy)azetidin-3-yl]amino}-2-oxoethylidene]amino}oxy)acetic acid
• 2-[[(Z)-[1-(2-Amino-4-thiazolyl)-2-[[(3S)-2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]acetic acid
• Acetic acid, (((1-(2-amino-4-thiazolyl)-2-((2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl)amino)-2-oxoethylidene)amino)oxy)-, (S-(Z))-
• Acetic acid, 2-[[(Z)-[1-(2-amino-4-thiazolyl)-2-[[(3S)-2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-
• Acetic acid, [[(Z)-[1-(2-amino-4-thiazolyl)-2-[[(3S)-2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-
• Tigemonam [INN]
• Tigemonamum
• Tigemonamum [Latin]
• Tigemonam
• Antibiotic SQ-30213
• SQ-30213
• Sulfuric acid [(3S)-3-[[2-(2-aminothiazol-4-yl)-2-[(Z)-carboxymethyloxyimino]-1-oxyethyl]amino]-4,4-dimethyl-2-oxoazetidin-1-yl] ester
• Tigemom

Tigemonam

CAS: 102507-71-1

Tigemonam

Purity: ≥95%

Molecular weight: 437.41g/mol

Ref: 54-BUP04945

Tigemonam

CAS: 102507-71-1

Tigemonam is a synthetic beta-lactam antibiotic, which is derived from chemical synthesis processes. This compound operates by inhibiting bacterial cell wall synthesis, specifically targeting the penicillin-binding proteins (PBPs). The disruption of the cell wall synthesis ultimately leads to cell lysis and death of the bacteria, making it effective primarily against gram-negative bacterial infections.

Formula: C₁₂H₁₅N₅O₉S₂

Purity: Min. 95%

Molecular weight: 437.41 g/mol

Ref: 3D-AT168177

Tigemonam

CAS: 102507-71-1

Tigemonam is a monobactam, a novel orally administered monobactam that protects against gram-negative aerobic bacterial pathogens. Cost-effective and quality-assured.

Formula: C₁₂H₁₅N₅O₉S₂

Purity: 99.03% - >99.99%

Color and Shape: Solid

Molecular weight: 437.41

Ref: TM-T13926