CAS 1025687-58-4
:r788
Description:
R788, also known by its chemical name, is a small molecule that acts as a selective inhibitor of the enzyme spleen tyrosine kinase (Syk). This compound has garnered attention in the field of medicinal chemistry due to its potential therapeutic applications, particularly in the treatment of autoimmune diseases and certain types of cancer. R788 exhibits characteristics such as good solubility in organic solvents and moderate stability under physiological conditions. Its mechanism of action involves the disruption of signaling pathways that are critical for the activation of immune cells, thereby modulating inflammatory responses. The compound has been studied in various preclinical and clinical settings, demonstrating efficacy in reducing disease symptoms in models of rheumatoid arthritis and other inflammatory conditions. Additionally, R788's pharmacokinetic profile suggests it can be administered orally, making it a convenient option for patients. As research continues, further insights into its safety, efficacy, and potential side effects are being explored to optimize its use in clinical applications.
- Fostamatinib sodium
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Found 7 products.
2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 6-[[5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-4-[(phosphonooxy)methyl]-, sodium salt (1:2)
CAS:Formula:C23H24FN6Na2O9PPurity:%Color and Shape:SolidMolecular weight:624.4232Sodium (6-((5-Fluoro-2-((3,4,5-Trimethoxyphenyl)Amino)Pyrimidin-4-Yl)Amino)-2,2-Dimethyl-3-Oxo-2,3-Dihydro-4H-Pyrido[3,2-B][1,4]Oxazin-4-Yl)Methyl Phosphate
CAS:Sodium (6-((5-Fluoro-2-((3,4,5-Trimethoxyphenyl)Amino)Pyrimidin-4-Yl)Amino)-2,2-Dimethyl-3-Oxo-2,3-Dihydro-4H-Pyrido[3,2-B][1,4]Oxazin-4-Yl)Methyl PhosphatePurity:98+%Molecular weight:624.42g/molFostamatinib Disodium
CAS:Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.Formula:C23H24FN6O9P·2NaPurity:96.13% - 99.09%Color and Shape:SolidMolecular weight:624.42R788 (Fostamatinib) Disodium
CAS:<p>R788 (Fostamatinib) Disodium is a drug that is used for the diagnosis of autoimmune diseases. It inhibits the activity of tyrosine kinases, which are enzymes that transmit signals in cells. Fostamatinib disodium has been shown to inhibit T-cell lymphomas in vivo and has been shown to have significant cytotoxicity against various leukemia cell lines. In vitro studies have shown that this drug is an inhibitor of effector proteins such as leukemia inhibitory factor and protein kinase C. The oral prodrug of R788 (fostamatinib) disodium has been found to be absorbed rapidly and to be glucuronide conjugated in humans. This drug also has pharmacokinetic properties that can be used to monitor its exposure in patients with autoimmune diseases and t-cell lymphomas.</p>Formula:C23H24FN6O9P·2NaPurity:Min. 95%Molecular weight:624.42 g/mol
![2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 6-[[5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidiny…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA008ST9.jpg&w=3840&q=75)
