CAS 102583-47-1
:Validamycin B
Description:
Validamycin B is a naturally occurring antibiotic compound primarily known for its fungicidal properties, particularly against various plant pathogens. It is derived from the fermentation of the bacterium Streptomyces hygroscopicus. The substance is characterized by its complex molecular structure, which includes multiple functional groups that contribute to its biological activity. Validamycin B exhibits a unique mechanism of action by inhibiting the synthesis of chitin, a critical component of fungal cell walls, thereby disrupting fungal growth and reproduction. This compound is often utilized in agricultural settings as a biopesticide, providing an environmentally friendly alternative to synthetic fungicides. Additionally, Validamycin B has been studied for its potential applications in medicine, particularly in the treatment of certain diseases caused by fungal infections. Its safety profile and efficacy make it a subject of interest in both agricultural and pharmaceutical research. Overall, Validamycin B represents a significant advancement in the development of natural products for disease management in crops and potential therapeutic applications.
Formula:C20H35NO14
InChI:InChI=1S/C20H35NO14/c22-2-5-1-7(12(27)15(30)10(5)25)21-9-11(26)6(3-23)19(17(32)14(9)29)35-20-18(33)16(31)13(28)8(4-24)34-20/h1,6-33H,2-4H2
InChI key:InChIKey=QYKWCMVFBWGYRE-UHFFFAOYSA-N
SMILES:O(C1C(CO)C(O)C(NC2C=C(CO)C(O)C(O)C2O)C(O)C1O)C3OC(CO)C(O)C(O)C3O
Synonyms:- Antibiotic T 7545B
- 1,5-Dideoxy-4-O-β-D-glucopyranosyl-5-(hydroxymethyl)-1-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-D-chiro-inositol
- D-chiro-Inositol, 1,5-dideoxy-4-O-β-D-glucopyranosyl-5-(hydroxymethyl)-1-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-
- Validamycin B
- D-chiro-Inositol, 1,5-dideoxy-4-O-β-D-glucopyranosyl-5-(hydroxymethyl)-1-[[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-, [1S-(1α,4α,5β,6α)]-
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Found 4 products.
Validamycin B
CAS:<p>Validamycin B is an aminoglycoside antibiotic, which is a type of product derived from the bacterium *Streptomyces hygroscopicus*. Its mode of action involves inhibiting the trehalase enzyme, an essential component for fungal cell viability, thereby disrupting the energy supply within the fungal cells. This disruption leads to impediments in fungal growth and proliferation.</p>Formula:C20H35NO14Purity:Min. 95%Molecular weight:513.5 g/mol
