CAS 102586-30-1

21-Norchol-5-ene-3,20,23-triol,24,24,24-trifluoro-23-(trifluoromethyl)-, (3b)- (9CI)

Description:

21-Norchol-5-ene-3,20,23-triol, 24,24,24-trifluoro-23-(trifluoromethyl)-, (3b)- (9CI) is a synthetic chemical compound characterized by its complex steroidal structure, which includes multiple functional groups such as hydroxyl (-OH) and trifluoromethyl (-CF3) groups. The presence of these groups suggests that the compound may exhibit unique biological activities and properties, potentially influencing its solubility, reactivity, and interaction with biological systems. The trifluoromethyl groups can enhance lipophilicity and metabolic stability, making the compound of interest in pharmaceutical research. Additionally, the compound's structural features indicate it may be a derivative of cholesterol, which could imply relevance in studies related to steroid hormones or cholesterol metabolism. Its specific stereochemistry, denoted by the (3b) designation, may also play a crucial role in determining its biological activity and receptor interactions. Overall, this compound represents a specialized area of study within medicinal chemistry and biochemistry, particularly in the context of drug design and development.

Formula: C₂₄H₃₄F₆O₃

NSC 12

CAS: 102586-30-1

NSC 12

Purity: ≥98%

Molecular weight: 484.52g/mol

Ref: 54-BUP21376

NSC 12

CAS: 102586-30-1

NSC 12 is an orally active pan-FGF trap that binds FGF2 and interferes with its interaction with FGFR1 with potential FGF-dependent antitumor activity.

Formula: C₂₄H₃₄F₆O₃

Purity: 99.51%

Color and Shape: Solid

Molecular weight: 484.52

Ref: TM-T36292

NSC12

CAS: 102586-30-1

NSC12 is a potent inhibitor of cell proliferation and tumor growth. It has been shown to inhibit muscle cell proliferation and induce apoptotic cell death. NSC12 binds to the hydroxyl group of HIF-1α, which prevents it from forming a complex with the transcriptional coactivator p300. This binding inhibits the transcriptional activity of HIF-1α, leading to decreased protein synthesis in cells and ultimately apoptosis. NSC12 has been shown to be an effective therapeutic agent for proliferative diabetic retinopathy in an experimental model.

Formula: C₂₄H₃₄F₆O₃

Purity: Min. 95%

Molecular weight: 484.52 g/mol

Ref: 3D-CEA58630