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CAS 102601-21-8

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na-benzoyl-dl-arginine 7-amido-4-*methyl-coumarin

Description:
Na-benzoyl-dl-arginine 7-amido-4-methyl-coumarin, commonly referred to as BAMC, is a synthetic compound that serves as a substrate in biochemical assays, particularly in the study of proteolytic enzymes. This compound features a coumarin moiety, which is known for its fluorescent properties, making it useful in fluorescence-based assays. The presence of the benzoyl and arginine groups contributes to its specificity and reactivity towards certain enzymes, particularly serine proteases. BAMC is typically used in research settings to monitor enzyme activity due to its ability to release a fluorescent product upon cleavage by the target enzyme. Its solubility in organic solvents and water makes it versatile for various experimental conditions. Additionally, the compound's stability under physiological conditions allows for reliable measurements in kinetic studies. Overall, BAMC is an important tool in enzymology and molecular biology, aiding in the understanding of enzyme mechanisms and interactions.
Formula:C23H26ClN5O4
InChI:InChI=1/C23H25N5O4.ClH/c1-14-12-20(29)32-19-13-16(9-10-17(14)19)27-22(31)18(8-5-11-26-23(24)25)28-21(30)15-6-3-2-4-7-15;/h2-4,6-7,9-10,12-13,18H,5,8,11H2,1H3,(H,27,31)(H,28,30)(H4,24,25,26);1H
SMILES:Cc1cc(=O)oc2cc(ccc12)N=C(C(CCCNC(=N)N)N=C(c1ccccc1)O)O.Cl
Synonyms:
  • N-{4-[(diaminomethylidene)amino]-1-[(4-methyl-2-oxo-2H-chromen-7-yl)carbamoyl]butyl}benzamide hydrochloride
  • Bz-Dl-Arg-Amc Hcl
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