CAS 102625-64-9

Pantoprazole sulfide

Description:

Pantoprazole sulfide, with the CAS number 102625-64-9, is a chemical compound that is a derivative of pantoprazole, a proton pump inhibitor commonly used to treat gastroesophageal reflux disease (GERD) and other conditions related to excessive stomach acid. This compound is characterized by its sulfinyl functional group, which contributes to its pharmacological properties. Pantoprazole sulfide is typically a white to off-white crystalline solid, exhibiting low solubility in water but higher solubility in organic solvents. It is known for its stability under acidic conditions, which is essential for its function in inhibiting gastric acid secretion. The compound operates by irreversibly binding to the proton pump in the stomach lining, thereby reducing acid production. Its pharmacokinetics involve rapid absorption and metabolism, primarily in the liver, leading to its active metabolites. As with many pharmaceuticals, safety and efficacy are paramount, and pantoprazole sulfide is subject to regulatory scrutiny to ensure it meets health standards for therapeutic use.

Formula: C₁₆H₁₅F₂N₃O₃S

InChI: InChI=1/C16H15F2N3O3S/c1-22-13-5-6-19-12(14(13)23-2)8-25-16-20-10-4-3-9(24-15(17)18)7-11(10)21-16/h3-7,15H,8H2,1-2H3,(H,20,21)

InChI key: InChIKey=UKILEIRWOYBGEJ-UHFFFAOYSA-N

SMILES: S(CC1=C(OC)C(OC)=CC=N1)C=2NC=3C(N2)=CC(OC(F)F)=CC3

Synonyms:

• 1H-Benzimidazole, 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-
• 1H-Benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-
• 5-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridyl)methyl]thio]-1H-benzimidazole
• 5-(Difluoromethoxy)-2-{[( 3,4 Dimethoxypyridin-2-yl) methyl] thio}-1H-benzimidazolee
• 5-Difluoromethoxy-2-[(3,4-methoxy-2-pyridinylmethyl thio)-1H-benzimidozole
• 5-Diflyoromethoxy-2-[(3,4-dimethoxy-2-pyridinyl)methyl]thio-1H-benzimidazole
• 6-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-1H-benzimidazole
• 6-(difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole
• H 258/28
• Pantoprazole sulfide
• Pantoprazole thioether
• 5-Difluoromethoxy-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]thio}-1H-benzimidazole
• 5-(Difluoromethoxy)-2[[(3,4-dimethoxy-2-pyridinyl)methyl]-thio]-1H-benzimidazole
• 5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulphanyl}-1H-benzimidazole
• 5-DIFLUOROMETHOXY-2-[(3,4-DIMETHOXY-2-PYRIDINYL)METHYL] THIO-1H-BENZIMIDAZOLE =98%
• 5-(Difluoromethoxy)-2-{[3,4-di
• 5-(DIFLUOROMETHOXY)-2-{[3,4-DIMETHOXY-2-PYRIDINYL)METHYL]THIO}IH-BENZIMIDAZOLE
• 5-DIFLUORMETHOXY-2[(3,4-DIMETHOXY-2-PRIDIXY)METHYLTHIO]-1H-BENZIMIDAZOLE
• 5-(Difluoromethoxy)-2-{[(3,4-dimethoxy-2-pyridinyl)-methyl]-thio}-1H-benzim
• 5-Difluoromethoxy-2-(((3,4-Dimethoxy-2-pyridinyl)methyl)thio)-1H-Benzimidazole (Pantaprazole intermediate)
• 5-Difluoromethoxy-2-{[(3,4-dim
• 5-(DIFLUOROMETHOXY)-2-[[3,4-DIMETHOXY-2-PYRIDINYL)-METHYL]-THIO]-1H-BENZIMIDAZOLE (PANTOPRAZOLE SULPHIDE COMPOUND)
• 5-Difluoromethoxy-2-(3,4-dimethoxy-pyridin-2-ylmethylsulfanyl)-1H-benzoimidazole
• 5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]thio}-1H-benzimidazole

Pantoprazole Sulfide

CAS: 102625-64-9

Formula: C₁₆H₁₅F₂N₃O₃S

Purity: >98.0%(T)(HPLC)

Color and Shape: Light orange to Light red powder to crystal

Molecular weight: 367.37

Ref: 3B-P2066

Pantoprazole Related Compound B (5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-1H-benzimidazole)

CAS: 102625-64-9

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₁₆H₁₅F₂N₃O₃S

Color and Shape: Off-White Light Brown Crystalline Powder

Molecular weight: 367.08022

Ref: 45-1494910

1H-Benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-

CAS: 102625-64-9

Formula: C₁₆H₁₅F₂N₃O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 367.3704

Ref: IN-DA0007YM

Pantoprazole EP Impurity B (Pantoprazole USP Related Compound B, Pantoprazole Sulfide)

CAS: 102625-64-9

Formula: C₁₆H₁₅F₂N₃O₃S

Color and Shape: Off-White Solid

Molecular weight: 367.37

Ref: 4Z-P-0111

5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]thio}-1H-benzimidazole

CAS: 102625-64-9

5-(Difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]thio}-1H-benzimidazole

Purity: 98%

Molecular weight: 367.37g/mol

Ref: 54-PC3237

Pantoprazole EP Impurity B

Controlled Product

CAS: 102625-64-9

Formula: C₁₆H₁₅F₂N₃O₃S

Color and Shape: Neat

Molecular weight: 367.37

Ref: 86-MM0099.03

Pantoprazole Sulfide

CAS: 102625-64-9

Pantoprazole sulfide, a metabolite of pantoprazole, is formed by CYP2C19 and CYP3A4 enzymes.

Formula: C₁₆H₁₅F₂N₃O₃S

Color and Shape: Solid

Molecular weight: 367.37

Ref: TM-T37247

Pantoprazole EP Impurity B-d6 (Pantoprazole USP Related Compound B-d6, Pantoprazole Sulfide-d6)

CAS: 102625-64-9

Formula: C₁₆H₉D₆F₂N₃O₃S

Molecular weight: 373.41

Ref: 4Z-P-0185

5-Difluoromethoxy-2-[(3,4-dimethoxy-2-pyridinyl)methyl]thio-1H-benzimidazole

CAS: 102625-64-9

Purity: 95.0%

Molecular weight: 367.3699951171875

Ref: 10-F049541

Pantoprazole EP Impurity B

CAS: 102625-64-9

Formula: C₁₆H₁₅F₂N₃O₃S

Molecular weight: 367.37

Ref: ST-EA-CP-P15002

Pantoprazole Sulfide

CAS: 102625-64-9

Impurity Pantoprazole EP Impurity B/ Pantoprazole USP Related Compound B
Applications Pantoprazole Sulfide (Pantoprazole EP Impurity B) is a metabolite of Pantoprazole (P183000), an antiulcerative, gastric pump inhibitor.

Formula: C₁₆H₁₅F₂N₃O₃S

Color and Shape: Neat

Molecular weight: 367.37

Ref: TR-P183020

Pantoprazole sulphide

CAS: 102625-64-9

Pantoprazole sulphide is a benzimidazole derivative that has been synthesized in an asymmetric synthesis. The purified compound was characterized by its nmr spectra, which showed the presence of the carboethoxy group and the chromatographic method. The compound belongs to a family of inhibitors known as benzimidazole derivatives and has shown inhibitory activity against a number of bacterial species including Staphylococcus aureus, Clostridium perfringens, and Mycobacterium tuberculosis. Pantoprazole sulphide has been used as an inhibitor to treat gastric acid pump disorders such as Zollinger-Ellison syndrome. It is also used for treating pathological conditions such as duodenal ulcers or gastroesophageal reflux disease.

Formula: C₁₆H₁₅F₂N₃O₃S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 367.37 g/mol

Ref: 3D-ID57911