CAS 102625-70-7: Pantoprazole
Description:Pantoprazole is a proton pump inhibitor (PPI) primarily used to treat gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid production. Its chemical formula is C16H15F2N3O4S, and it features a sulfoxide group, a pyridine ring, and a benzimidazole moiety, which contribute to its pharmacological activity. Pantoprazole works by irreversibly inhibiting the H+/K+ ATPase enzyme in the gastric parietal cells, effectively reducing gastric acid secretion. It is typically administered in its enteric-coated form to ensure stability and absorption in the gastrointestinal tract. The substance is characterized by its relatively low solubility in water, which can affect its bioavailability. Pantoprazole is generally well-tolerated, but potential side effects may include headache, gastrointestinal disturbances, and, with long-term use, an increased risk of certain infections and nutrient deficiencies. Its pharmacokinetics involve rapid absorption, with peak plasma concentrations occurring within a few hours post-administration, and it is primarily metabolized in the liver.
Formula:C16H15F2N3O4S
InChI:InChI=1S/C16H15F2N3O4S/c1-23-13-5-6-19-12(14(13)24-2)8-26(22)16-20-10-4-3-9(25-15(17)18)7-11(10)21-16/h3-7,15H,8H2,1-2H3,(H,20,21)
InChI key:InChIKey=IQPSEEYGBUAQFF-UHFFFAOYSA-N
SMILES:O=S(C1=NC=2C=C(OC(F)F)C=CC2N1)CC3=NC=CC(OC)=C3OC
- Synonyms:
- 1H-Benzimidazole, 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-
- 1H-Benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-
- 2-[[(3,4-Dimethoxypyridin-2-yl)methyl]sulfinyl]-5-difluoromethoxy-1H-benzimidazole
- 5-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole
- 5-Difluoromethoxy-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl }-1H-benzimidazole
- 6-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
- 6-(difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
- Altopan
- By 1023
- Controloc Control
- See more synonyms
- Pantecta Control
- Pantocid
- Pantoloc Control
- Pantopan
- Pantozol
- Pantozol Control
- Protium
- Protium (pharmaceutical)
- Skf 96022
- Somac Control
- Zovanta
- Pantoprazole