CAS 102676-47-1: Fadrozole

Description: Fadrozole is a synthetic compound primarily recognized as an aromatase inhibitor, which means it inhibits the enzyme aromatase responsible for converting androgens to estrogens. This characteristic makes it significant in the treatment of hormone-dependent conditions, particularly certain types of breast cancer. The chemical structure of fadrozole includes a pyridine ring, contributing to its pharmacological properties. It is typically administered orally and has been studied for its potential in both human and veterinary medicine, particularly in the context of managing estrogen-related disorders. Fadrozole exhibits a relatively high affinity for the aromatase enzyme, leading to a decrease in estrogen levels in the body. Its pharmacokinetics involve absorption, distribution, metabolism, and excretion, which are crucial for determining its therapeutic efficacy and safety profile. As with many pharmaceuticals, potential side effects may include hormonal imbalances and other related symptoms, necessitating careful monitoring during treatment. Overall, fadrozole represents an important tool in endocrine therapy, particularly in oncology.

Formula: C₁₄H₁₃N₃

InChI: InChI=1S/C14H13N3/c15-8-11-4-6-12(7-5-11)14-3-1-2-13-9-16-10-17(13)14/h4-7,9-10,14H,1-3H2

InChI key: InChIKey=CLPFFLWZZBQMAO-UHFFFAOYSA-N

SMILES: N#CC1=CC=C(C=C1)C2N3C=NC=C3CCC2

Synonyms:

• 4-(5,6,7,8-Tetrahydroimidazo[1,5-A]Pyridin-5-Yl)Benzonitrile
• Benzonitrile, 4-(5,6,7,8-tetrahydroimidazo(1,5-a)pyridin-5-yl)-
• Ccris 8823
• Fadrozol
• Fadrozol [INN-Spanish]
• Fadrozole [INN]
• Fadrozolum
• Fadrozolum [INN-Latin]
• Imidazo[1,5-a]pyridine, benzonitrile deriv.
• Unii-H3988M64Pu

Benzonitrile, 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)-

CAS: 102676-47-1

• Formula: C₁₄H₁₃N₃
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 223.27311999999992

Fadrozole

CAS: 102676-47-1

• Purity: 98%
• Molecular weight: 223.27g/mol

Fadrozole

CAS: 102676-47-1

• Formula: C₁₄H₁₃N₃
• Molecular weight: 223.27

Fadrozole

CAS: 102676-47-1

Fadrozole is a nonsteroidal aromatase inhibitor with potential antineoplastic activity(IC50 : 6.4 nM)

• Formula: C₁₄H₁₃N₃
• Purity: 99.47%
• Color and Shape: Solid
• Molecular weight: 223.27

Fadrozole

CAS: 102676-47-1

Versatile small molecule scaffold

• Formula: C₁₄H₁₃N₃
• Purity: Min. 95%
• Molecular weight: 223.27 g/mol