CAS 1026785-59-0

VX-222

CAS: 1026785-59-0

Formula: C₂₅H₃₅NO₄S

Purity: 99%

Color and Shape: Solid

Molecular weight: 445.6147

Ref: IN-DA008TKL

cis-Lomibuvir

CAS: 1026785-59-0

cis-Lomibuvir (cis-VX-222) is a selective HCV NS5B RdRp inhibitor with a Kd of 17 nM and an EC50 of 5.2 nM, targeting thumb pocket 2.

Formula: C₂₅H₃₅NO₄S

Color and Shape: Solid

Molecular weight: 445.61

Ref: TM-T73814

Lomibuvir (VX-222)

CAS: 1026785-59-0

Lomibuvir is a viral inhibitor that prevents the replication of viruses by binding to the protein inhibitors of viral replication. It also inhibits the ns3 protease of wild-type viruses and their ability to replicate. Lomibuvir has been shown to be effective in vitro against hepatitis A virus, hepatitis B virus, and HIV. Animal studies have shown that lomibuvir is able to inhibit the replication of human liver cells infected with the Hepatitis C virus. Lomibuvir binds to ribonucleic acid (RNA) and prevents it from being translated into proteins.
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-->Lomibuvir has good pharmacokinetic properties and can be administered orally or intravenously.

Formula: C₂₅H₃₅NO₄S

Purity: Min. 95%

Molecular weight: 445.61 g/mol

Ref: 3D-BRB78559