CAS 102686-43-1

Atrial Natriuretic Factor (3-28) (human)

Description:

Atrial Natriuretic Factor (3-28) (human), with the CAS number 102686-43-1, is a peptide hormone that plays a crucial role in cardiovascular homeostasis. It is derived from the larger precursor pro-atrial natriuretic peptide (pro-ANP) and consists of 26 amino acids, specifically the C-terminal fragment. This peptide is primarily produced in the atria of the heart and is released in response to increased blood volume and pressure. Its main characteristics include its ability to promote natriuresis, which is the excretion of sodium through urine, and diuresis, the increased production of urine. Additionally, it acts as a vasodilator, helping to lower blood pressure by relaxing blood vessels. Atrial Natriuretic Factor (3-28) also inhibits the renin-angiotensin-aldosterone system, further contributing to its role in fluid balance and blood pressure regulation. Due to its physiological significance, it is of interest in research related to heart failure, hypertension, and other cardiovascular disorders.

Formula: C₁₁₈H₁₈₇N₄₃O₃₆S₃

Synonyms:

• H-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH (Disulfide bond)

L-Tyrosine, L-arginyl-L-arginyl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanylglycylglycyl-L-arginyl-L-methionyl-L-α-aspartyl-L-arginyl-L-isoleucylglycyl-L-alanyl-L-glutaminyl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-asparaginyl-L-seryl-L-phenylalanyl-L-arginyl-, cyclic (5→21)-disulfide

CAS: 102686-43-1

Formula: C₁₁₈H₁₈₇N₄₃O₃₆S₃

Molecular weight: 2880.2089

Ref: IN-DA00083X

Atrial natriuretic peptide (3-28) (human)

CAS: 102686-43-1

Atrial natriuretic peptide (3-28) (human) (ANP (3-28) (human)), a peptide hormone produced by the atrial myocardium, plays a critical role in the regulation of

Formula: C₁₁₈H₁₈₇N₄₃O₃₆S₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 2880.21

Ref: TM-T80438

ANP (3-28) (Human, Porcine, Bovine)

CAS: 102686-43-1

ANP (3-28) is a peptide that belongs to the class of activators. It is a ligand for the G protein-coupled receptor ANP receptor and also binds to the N-type calcium channel. ANP (3-28) has been shown to activate potassium channels in cell culture, and it has been used as a research tool for studying ion channels. This peptide has also been found to inhibit the growth of various types of cancer cells, including those from breast, prostate, and colon cancers.

Formula: C₁₁₈H₁₈₇N₄₃O₃₆S₃

Purity: Min. 95%

Molecular weight: 2,880.26 g/mol

Ref: 3D-ANP-3755-PI

Atrial Natriuretic Factor (3-28) (human, bovine, porcine)

CAS: 102686-43-1

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Formula: C₁₁₈H₁₈₇N₄₃O₃₆S₃

Purity: Min. 95%

Molecular weight: 2,880.21 g/mol

Ref: 3D-FA108415