CAS 1027-14-1

2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide monohydrochloride

Description:

2-(Diethylamino)-N-(2,4,6-trimethylphenyl)acetamide monohydrochloride, with the CAS number 1027-14-1, is a chemical compound characterized by its amide functional group and the presence of a diethylamino moiety. This substance typically appears as a white to off-white crystalline solid and is soluble in water and various organic solvents, which is indicative of its polar nature due to the amine and amide functionalities. The compound is often utilized in pharmaceutical applications, particularly as an intermediate in the synthesis of various drugs. Its structure features a bulky aromatic ring, which contributes to its lipophilicity, while the diethylamino group enhances its basicity. The hydrochloride form indicates that it is a salt, which can affect its stability and solubility profile. Safety data should be consulted for handling and exposure guidelines, as with any chemical substance, to ensure proper laboratory practices.

Formula: C₁₅H₂₅ClN₂O

InChI: InChI=1/C15H24N2O.ClH/c1-6-17(7-2)10-14(18)16-15-12(4)8-11(3)9-13(15)5;/h8-9H,6-7,10H2,1-5H3,(H,16,18);1H

InChI key: InChIKey=KOOGJYYOMPUGCW-UHFFFAOYSA-N

SMILES: CCN(CC)CC(=Nc1c(C)cc(C)cc1C)O.Cl

Synonyms:

• 2-(Diethylamino)-N-mesitylacetamide hydrochloride
• 2-Diethylamino-2',4',6'-trimethylacetanilide hydrochloride
• 2-Diethylamino-N-(2,4,6-trimethyl-phenyl)-acetamide; hydrochloride
• Acetamide, 2-(diethylamino)-N-(2,4,6-trimethylphenyl)-, hydrochloride (1:1)
• Acetamide, 2-(diethylamino)-N-(2,4,6-trimethylphenyl)-, monohydrochloride
• Acetamide, 2-(diethylamino)-N-(2,4,6-trimethylphenyl)-, monohydrochloride (9CI)
• Acetanilide, 2-(diethylamino)-2',4',6'-trimethyl-, hydrochloride
• Acetanilide, 2-(diethylamino)-2',4',6'-trimethyl-, monohydrochloride (8CI)
• Acetanilide, 2-(diethylamino)-2′,4′,6′-trimethyl-, monohydrochloride
• Acetanilide, 2-diethylamino-2′,4′,6′-trimethyl-, hydrochloride
• Diethylaminoacetyl 2,4,6-trimethyl-aniline hydrochloride
• Mesidicaine hydrochloride
• Mesocain
• Mesocaine
• Mesokain
• N,N-diethyl-2-oxo-2-[(2,4,6-trimethylphenyl)amino]ethanaminium chloride
• N-sym-Trimethylphenyldiethylaminoacetamide hydrochloride
• Trimecaine HCl
• Trimecaine Monohydrochloride
• Trimecaine hydrochloride
• Trimekain hydrochloride

Acetamide, 2-(diethylamino)-N-(2,4,6-trimethylphenyl)-, hydrochloride (1:1)

CAS: 1027-14-1

Formula: C₁₅H₂₅ClN₂O

Purity: 97%

Color and Shape: Solid

Molecular weight: 284.8248

Ref: IN-DA00085Q

Trimecaine Hydrochloride

CAS: 1027-14-1

Applications A local anesthetic and cardial antiarrhythmic. It used in epidural postoperative analgesia after major urological procedures in combination with morphine.
References Dostalova, V. et al.: Bratisl. Lek. Listy, 109, 11 (2008); Gendenshtein, E.I. et al.: Kardiol., 16, 128 (1976); Stolc, S. et al.: Eur. J. Pharmacol., 164, 249 (1989);

Formula: C₁₅H₂₄N₂O·ClH

Color and Shape: Neat

Molecular weight: 284.82

Ref: TR-T795620

Trimecaine hydrochloride

CAS: 1027-14-1

Trimecaine hydrochloride is a local anaesthetic that can be used in the treatment of pain. It is a non-narcotic, anti-inflammatory drug that is also useful as an antipruritic and as a topical agent for the relief of itching. Trimecaine hydrochloride blocks nerve conduction by inhibiting sodium ion influx across the neuronal membrane. This prevents activation of voltage-gated sodium channels and subsequent depolarization, which leads to decreased nerve conduction. Trimecaine hydrochloride is not absorbed through intact skin and does not cause systemic toxicity or respiratory depression.

Formula: C₁₅H₂₄N₂O•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 284.82 g/mol

Ref: 3D-FT28512

Trimecaine Hydrochloride

CAS: 1027-14-1

Formula: C₁₅H₂₄N₂OHCl

Molecular weight: 248.37 : 36.5

Ref: ST-EA-CP-T107001