CAS 1027-28-7: N-Acetyl-3,5-diiodo-L-tyrosine
Description:N-Acetyl-3,5-diiodo-L-tyrosine is a modified amino acid derivative of tyrosine, characterized by the presence of two iodine atoms at the 3 and 5 positions of the aromatic ring, along with an acetyl group attached to the amino group. This compound is notable for its potential applications in biochemical research and pharmaceuticals, particularly in studies related to thyroid hormones, as iodine is a critical component of these hormones. The acetylation enhances its solubility and stability compared to its parent compound, L-tyrosine. N-Acetyl-3,5-diiodo-L-tyrosine exhibits properties typical of halogenated aromatic compounds, including increased lipophilicity and potential biological activity. It may also participate in various chemical reactions, such as electrophilic substitutions, due to the presence of the iodine substituents. Additionally, its structure allows for interactions with biological systems, making it a subject of interest in medicinal chemistry and drug design. Safety and handling precautions should be observed, as with all chemical substances, due to potential toxicity associated with iodine-containing compounds.
Formula:C11H11I2NO4
InChI:InChI=1S/C11H11I2NO4/c1-5(15)14-9(11(17)18)4-6-2-7(12)10(16)8(13)3-6/h2-3,9,16H,4H2,1H3,(H,14,15)(H,17,18)/t9-/m0/s1
InChI key:InChIKey=CDXURJOCZAIXFK-VIFPVBQESA-N
SMILES:O=C(O)C(NC(=O)C)CC1=CC(I)=C(O)C(I)=C1
- Synonyms:
- (2S)-2-Acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid
- 2-(Acetylamino)-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid
- 3,5-Diiodo-N-Acetyl-L-Tyrodine
- 3,5-Diiodo-N-acetyl-<span class="text-smallcaps">L</span>-tyrosine
- <span class="text-smallcaps">L</span>-Tyrosine, N-acetyl-3,5-diiodo-
- N-Acetyl-3,5-diiodo-<span class="text-smallcaps">L</span>-tyrosine
- N-Acetyl-3,5-diiodo-L-tyrosine
- N-Acetyl-3,5-diiodotyrosine
- NSC 76100
- Tyrosine, N-acetyl-3,5-diiodo-, <span class="text-smallcaps">L</span>-
- See more synonyms
- 3,5-Diiodo-N-acetyl-L-tyrosine
- Tyrosine, N-acetyl-3,5-diiodo-, L-
- L-Tyrosine, N-acetyl-3,5-diiodo-