CAS 102731-45-3

7-DEAZAGUANOSINE

Description:

7-Deazaguanosine is a modified nucleoside that is structurally related to guanosine, where the nitrogen atom at the 7-position of the purine ring is replaced by a carbon atom. This modification alters its biochemical properties and interactions. The substance is known for its role in various biochemical pathways, particularly in nucleic acid metabolism and as a potential therapeutic agent. It exhibits characteristics typical of nucleosides, such as the ability to participate in hydrogen bonding and base pairing, albeit with altered affinities due to the structural modification. 7-Deazaguanosine can influence RNA synthesis and stability, making it of interest in research related to antiviral and anticancer therapies. Additionally, it may serve as a substrate for certain enzymes, impacting cellular processes. Its CAS number, 102731-45-3, allows for precise identification in chemical databases, facilitating research and application in medicinal chemistry and biochemistry. Overall, 7-deazaguanosine represents a significant compound in the study of nucleoside analogs and their potential therapeutic uses.

Formula: C₁₁H₁₄N₄O₅

InChI: InChI=1/C11H14N4O5/c12-11-14-5-3(1-13-6(5)10(19)15-11)9-8(18)7(17)4(2-16)20-9/h1,3-4,7-9,16-18H,2H2,(H3,12,14,15,19)/t3?,4-,7+,8?,9+/m1/s1

Synonyms:

• 2-Amino-7-(Beta-D-Ribofuranosyl)[3,2-D]Pyrimidin-4-One
• 2-Amino-7-(Beta-D-Ribofuranosyl)Pyrrolo[3,2-D]Pyrimidin-4-One
• 9-Deazaguanosine
• 2-Amino-7-(D-ribofuranosyl[3,2-d]pyrimidin-4-one
• 9-Deaza-D-guanosine
• 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro-7-β-D-ribofuranosyl-
• 2-AMino-1,5-dihydro-7-β-D-ribofuranosyl-4H-pyrrolo[3,2-d]pyriMidin-4-one
• 7-DEAZAGUANOSINE

9-Deazaguanosine

CAS: 102731-45-3

Formula: C₁₁H₁₄N₄O₅

Color and Shape: Solid

Molecular weight: 282.2527

Ref: IN-DA00087Z

9-Deazaguanosine

CAS: 102731-45-3

Ref: 7W-GN7672

9-Deazaguanosine

CAS: 102731-45-3

9-Deazaguanosine is a naturally occurring purine, which has been shown to inhibit the binding of adenosine deaminase enzyme. This enzyme is responsible for the conversion of adenosine to inosine, and plays a role in the replication of viruses. 9-Deazaguanosine has also been shown to have an inhibitory effect on trichomonas vaginalis, benzyl groups, and anomers. The hydroxyl group on 9-Deazaguanosine interacts with mammalian cells which may be related to its inhibitory effect on leishmania and hepatitis.

Formula: C₁₁H₁₄N₄O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 282.25 g/mol

Ref: 3D-ND06109

9-Deazaguanosine

Controlled Product

CAS: 102731-45-3

Stability Hygroscopic
Applications A guanosine analogue.
References Girgis, N., et al.: J. Med. Chem., 33, 2750 (1990), Lin, C., et al.: Biochem., 33, 2703 (1994),

Formula: C₁₁H₁₄N₄O₅

Color and Shape: Neat

Molecular weight: 282.25

Ref: TR-D201400