CAS 102771-26-6

4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine

Description:

4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine, with the CAS number 102771-26-6, is a chemical compound that belongs to the class of benzodiazepines, which are known for their psychoactive properties. This compound features a complex structure that includes a benzodiazepine core fused with a dioxole ring, contributing to its unique chemical behavior. The presence of the methyl group enhances its lipophilicity, potentially influencing its pharmacokinetic properties. The amine functional group on the benzene ring suggests that it may participate in hydrogen bonding, which can affect its solubility and reactivity. Such compounds are often studied for their potential therapeutic applications, including anxiolytic, sedative, or anticonvulsant effects. However, the specific biological activity and safety profile of this compound would require further investigation through experimental studies. Overall, its intricate structure and functional groups make it a subject of interest in medicinal chemistry and pharmacology.

Formula: C₁₇H₁₅N₃O₂

InChI: InChI=1S/C17H15N3O2/c1-10-6-12-7-15-16(22-9-21-15)8-14(12)17(20-19-10)11-2-4-13(18)5-3-11/h2-5,7-8H,6,9,18H2,1H3

InChI key: InChIKey=LFBZZHVSGAHQPP-UHFFFAOYSA-N

SMILES: CC=1CC2=C(C(=NN1)C3=CC=C(N)C=C3)C=C4C(=C2)OCO4

Synonyms:

• 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine
• 4-(8-methyl-9H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl)aniline
• 4-(8-methyl-9H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl)aniline hydrochloride (1:1)
• 9H-1,3-Dioxolo[4,5-h][2,3]benzodiazepine, benzenamine deriv.
• Benzenamine, 4-(8-methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-
• Gyki 52466
• Gyki 52466 Hydrochloride

4-(8-Methyl-9H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,2]diazepin-5-yl)aniline

CAS: 102771-26-6

Formula: C₁₇H₁₅N₃O₂

Color and Shape: Solid

Molecular weight: 293.3199

Ref: IN-DA0008CN

4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine

Controlled Product

CAS: 102771-26-6

Formula: C₁₇H₁₅N₃O₂

Color and Shape: Neat

Ref: TR-M303695

4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine

CAS: 102771-26-6

4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine is a drug that was originally synthesized to study the mechanisms of depression. It has been shown to alter energy metabolism and locomotor activity in rats. 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine binds to the cation channel and induces neuronal death by causing an increase in oxidative stress and inhibition of atp synthesis. Chronic exposure to this compound leads to rotarod impairments and decreased atp levels in rat brain cells. This drug also has pharmacokinetic properties as a substrate for the neurotransmitter gamma aminobutyric acid (GABA).

Formula: C₁₇H₁₅N₃O₂

Purity: Min. 95%

Molecular weight: 293.32 g/mol

Ref: 3D-CEA77126

GYKI-52466

CAS: 102771-26-6

GYKI-52466: non-competitive AMPA antagonist, IC50: 10-20 μM for AMPA. Also relaxes muscles, treats seizures, neuroprotects, reduces anxiety.

Formula: C₁₇H₁₅N₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 293.32

Ref: TM-T21449