CAS 1027734-01-5

5'-O-DMT-N6-Acetyl-2'-deoxyadenosine 3'-CE phosphoramidite

Description:

5'-O-DMT-N6-Acetyl-2'-deoxyadenosine 3'-CE phosphoramidite is a modified nucleoside used primarily in the field of oligonucleotide synthesis. This compound features a 5'-dimethoxytrityl (DMT) protecting group, which is crucial for the selective attachment of nucleotides during the synthesis process. The N6-acetyl modification enhances the stability and solubility of the nucleoside, while the 3'-CE (cyanoethyl) phosphoramidite group facilitates the formation of phosphodiester bonds, allowing for the efficient assembly of DNA strands. The presence of the 2'-deoxy configuration indicates that this nucleoside is a component of DNA rather than RNA. This compound is typically utilized in the synthesis of custom oligonucleotides for various applications, including molecular biology research, therapeutic development, and diagnostic assays. Its unique structural features contribute to its utility in producing high-fidelity and chemically modified oligonucleotides, which can be tailored for specific functions in genetic engineering and synthetic biology.

Formula: C₄₂H₅₀N₇O₇P

Synonyms:

• 5'-O-DMT-N6-Acetyl-2'-deoxyadenosine 3'-CE phosphoramidite
• Adenosine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
• 5'-O-DMT-N6-Acetyl-2'-deoxyadenosine 3'-CE phosphoramidite USP/EP/BP

(2R,3S,5R)-5-(6-Acetamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

CAS: 1027734-01-5

(2R,3S,5R)-5-(6-Acetamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

Purity: 97%

Molecular weight: 795.88g/mol

Ref: 54-OR1057141

Ac-dA Phosphoramidite

CAS: 1027734-01-5

Ac-dA Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.

Formula: C₄₂H₅₀N₇O₇P

Color and Shape: Solid

Molecular weight: 795.878

Ref: TM-T38425

N6-Acetyl-2'-deoxy-5'-O-DMT-adenosine 3'-CE phosphoramidite

CAS: 1027734-01-5

N6-Acetyl-2'-deoxy-5'-O-DMT-adenosine 3'-CE phosphoramidite is a novel, modified, activator with antiviral and anticancer properties. It is the monophosphate of the acetylated 2'-deoxyadenosine 3'-cyanoethylphosphoramidite and has been shown to be effective in inhibiting DNA synthesis in cell cultures. This product is synthesized using high purity reagents and purification techniques.

Formula: C₄₂H₅₀N₇O₇P

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 795.86 g/mol

Ref: 3D-PA09073