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CAS 102783-74-4

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2'-deoxyguanosine 5'-diphosphate sodium

Description:
2'-Deoxyguanosine 5'-diphosphate sodium, commonly referred to as dGDP, is a nucleotide that plays a crucial role in cellular metabolism and the synthesis of nucleic acids. It consists of a deoxyribose sugar, a guanine base, and two phosphate groups. The sodium salt form indicates that it is often used in biochemical applications where solubility is required. dGDP is involved in various biochemical pathways, including DNA synthesis and repair, serving as a substrate for DNA polymerases. Its structure allows it to participate in the formation of nucleic acid chains through phosphodiester bonds. The presence of the deoxyribose sugar distinguishes it from ribonucleotides, making it essential for DNA rather than RNA synthesis. In laboratory settings, dGDP can be utilized in enzymatic assays and studies of nucleotide metabolism. Its stability and reactivity are influenced by the surrounding pH and ionic strength, making it important to handle under controlled conditions to maintain its integrity for experimental purposes.
Formula:C10H15N5O10P2
InChI:InChI=1/C10H15N5O10P2/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(24-6)2-23-27(21,22)25-26(18,19)20/h3-6,16H,1-2H2,(H,21,22)(H2,18,19,20)(H3,11,13,14,17)/t4-,5+,6+/m0/s1
Synonyms:
  • 2-amino-9-{2-deoxy-5-O-[hydroxy(phosphonooxy)phosphoryl]pentofuranosyl}-3,9-dihydro-6H-purin-6-one
  • 2'-Deoxyguanosine 5'-(Trihydrogen Diphosphate)
  • 2'-Deoxyguanosine-5'-diphosphate,trisodium salt
  • dGDP.Na3
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