Blood-coagulation factor VIIa, specifically the human clone lHVII2463 protein moiety, is a crucial serine protease involved in the coagulation cascade, playing a vital role in hemostasis. It is activated by tissue factor, leading to the activation of factor X, which subsequently contributes to thrombin generation and fibrin formation. This protein is characterized by its glycoprotein structure, which includes several disulfide bonds that stabilize its conformation. Factor VIIa is essential for the initiation of blood coagulation, particularly in response to vascular injury. The human variant of this factor is produced in recombinant systems for therapeutic applications, particularly in treating bleeding disorders such as hemophilia. The CAS number 102786-61-8 identifies this specific protein, which is utilized in research and clinical settings. Its activity can be influenced by various factors, including the presence of inhibitors or co-factors, and it is subject to regulation by the body's anticoagulant mechanisms. Understanding its characteristics is crucial for developing treatments for coagulation disorders and improving surgical outcomes.

Blood-coagulationfactor VIIa (human clone lHVII2463 protein moiety) (9CI)

102786-61-8: Blood-coagulation factor VIIa, specifically the human clone lHVII2463 protein moiety, is a crucial serine protease involved in the coagulation cascade, playing a vital role in hemostasis. It is activated by tissue factor, leading to the activation of factor X, which subsequently contributes to thrombin generation and fibrin formation. This protein is characterized by its glycoprotein structure, which includes several disulfide bonds that stabilize its conformation. Factor VIIa is essential for the initiation of blood coagulation, particularly in response to vascular injury. The human variant of this factor is produced in recombinant systems for therapeutic applications, particularly in treating bleeding disorders such as hemophilia. The CAS number 102786-61-8 identifies this specific protein, which is utilized in research and clinical settings. Its activity can be influenced by various factors, including the presence of inhibitors or co-factors, and it is subject to regulation by the body's anticoagulant mechanisms. Understanding its characteristics is crucial for developing treatments for coagulation disorders and improving surgical outcomes.

<p>HUMAN COAGULATION FACTOR VIIA (RDNA) CRS</p>

CAS 102786-61-8

Blood-coagulationfactor VIIa (human clone lHVII2463 protein moiety) (9CI)

HUMAN COAGULATION FACTOR VIIA (RDNA) CRS

Ref: 41-Y0001663

Coagulation Factor VIIa For Bioassay (577 International Units )

Ref: 45-1311518

Coagulation Factor VIIa (Eptacog Alfa (Activated))

Ref: 45-1311500