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CAS 102814-06-2

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2-deoxyuridine-5-diphosphate sodium

Description:
2-Deoxyuridine-5-diphosphate sodium (dUDP) is a nucleotide analog that plays a crucial role in the biosynthesis of DNA. It is a derivative of uridine, where the hydroxyl group at the 2' position of the ribose sugar is replaced by a hydrogen atom, resulting in a deoxyribose structure. The diphosphate moiety indicates that it contains two phosphate groups, which are essential for its function in nucleotide metabolism and DNA synthesis. As a sodium salt, it is typically more soluble in aqueous solutions, facilitating its use in biochemical applications. dUDP is involved in the synthesis of deoxythymidine triphosphate (dTTP), a key building block for DNA. Its structural characteristics include a pyrimidine base (uracil), a deoxyribose sugar, and a diphosphate group, which contribute to its biochemical reactivity and interactions with enzymes such as deoxynucleoside triphosphate pyrophosphohydrolase. Overall, 2-deoxyuridine-5-diphosphate sodium is significant in molecular biology and biochemistry, particularly in studies related to DNA replication and repair mechanisms.
Formula:C9H14N2O11P2
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