CAS 102814-08-4

2'-deoxyuridine 5'-triphosphate

Description:

2'-Deoxyuridine 5'-triphosphate (dUTP) is a nucleotide that plays a crucial role in DNA synthesis and repair. It is a derivative of uridine, where the ribose sugar is modified to a deoxyribose, and it contains three phosphate groups attached to the 5' carbon. This structure allows dUTP to serve as a substrate for DNA polymerases during DNA replication. dUTP is also involved in the incorporation of uracil into DNA, which can lead to mutations if not properly regulated, as DNA typically contains thymine instead of uracil. The enzyme dUTPase hydrolyzes dUTP to dUMP and inorganic phosphate, thereby preventing the incorporation of uracil into DNA and maintaining genomic integrity. In addition to its biological significance, dUTP is utilized in various molecular biology techniques, including PCR and DNA sequencing, where it can be incorporated in place of dTTP to study the effects of uracil in DNA. Its CAS number, 102814-08-4, identifies it uniquely in chemical databases.

Formula: C₉H₁₅N₂NaO₁₄P₃

InChI: InChI=1/C9H15N2O14P3.Na/c12-5-3-8(11-2-1-7(13)10-9(11)14)23-6(5)4-22-27(18,19)25-28(20,21)24-26(15,16)17;/h1-2,5-6,8,12H,3-4H2,(H,18,19)(H,20,21)(H,10,13,14)(H2,15,16,17);

SMILES: c1cn(C2CC(C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)O)c(=O)nc1O.[Na]

Synonyms:

• 2-Deoxyuridine-5-triphosphoric acid sodium salt
• dUTP-Na
• 2'-Deoxyuridine 5'-(Tetrahydrogen Triphosphate)
• 2,4(1H,3H)-pyrimidinedione, 1-[2-deoxy-5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]pentofuranosyl]-, monosodium salt
• 2'-Deoxyuridine-5'-triphosphate,trisodium salt
• dUTP.Na3

2'-Deoxyuridine-5'-triphosphate trisodium salt, 95%

CAS: 102814-08-4

2'-Deoxyuridine-5'-triphosphate disodium salt is used in conjunction with uracil DNA glycosylase to prevent carryover contamination in PCR. The dUTP is substituted for dTTP in the PCR reaction, used to study the distribution, specificity and kinetics of deoxyuridine 5?-triphosphate nucleotidohydro

Formula: C₉H₁₅N₂O₁₄P₃

Purity: 95%

Color and Shape: White, Powder

Molecular weight: 468.14

Ref: 02-J64716

Uridine5'-(tetrahydrogen triphosphate), 2'-deoxy-, trisodium salt (9CI)

CAS: 102814-08-4

Formula: C₉H₁₂N₂Na₃O₁₄P₃

Purity: 95%

Color and Shape: Liquid

Molecular weight: 534.0872

Ref: IN-DA00H9V3

2''-Deoxyuridine-5''-triphosphate trisodium salt (dUTP)

CAS: 102814-08-4

Formula: C₉H₁₅N₂Na₂O₁₄P₃

Molecular weight: 514.12

Ref: 7W-GN6513

dUTP trisodium

CAS: 102814-08-4

dUTP trisodium (Deoxyuridine triphosphate) is a deoxyuridine phosphate having a triphosphate group at the 5'-position and can be used for PCR.

Formula: C₉H₁₂N₂Na₃O₁₄P₃

Purity: 100.00%

Color and Shape: Solid

Molecular weight: 534.09

Ref: TM-T38427

dUTP trisodium

CAS: 102814-08-4

dUTP trisodium

Purity: ≥98%

Molecular weight: 534.09g/mol

Ref: 54-BUP06512

2'-Deoxyuridine-5'-triphosphate trisodium

CAS: 102814-08-4

2'-Deoxyuridine-5'-triphosphate trisodium salt is a fluorophore that is excited by the absorption of light at wavelengths of 365 nm. The emission spectrum ranges from 380 to 500 nm and has a maximum at 480 nm. 2'-Deoxyuridine-5'-triphosphate trisodium salt can be used as a labeling agent for metal ion, molecule, or macrocyclic ligand. It can also be used as an acceptor in fluorescence energy transfer experiments.

Formula: C₉H₁₅N₂O₁₄P₃•Na₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 537.11 g/mol

Ref: 3D-ND08736

2'-Deoxyuridine-5'-triphosphate Trisodium Salt >90% (contains ammonium salt)

Controlled Product

CAS: 102814-08-4

Stability Hygroscopic
Applications 2'-Deoxyuridine-5'-triphosphate trisodium salt (CAS# 102814-08-4) is a nucleotide and the sodium salt of dUTP, used as an analyte in biological assays.
References Lisitsa, T. S.; et al.: Biophys., 62, 366 (2017); Lacroix, J.; et al.: Small, 12, 5963 (2016).

Formula: C₉H₁₅N₂O₁₄P₃

Color and Shape: Neat

Molecular weight: 468.142

Ref: TR-D288038

Sodium ((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl triphosphate

CAS: 102814-08-4

Purity: 95%

Molecular weight: 556.067

Ref: 10-F982303