CAS 102832-10-0

2'-deoxyadenosine 3'-monophosphate*sodium

Description:

2'-Deoxyadenosine 3'-monophosphate sodium, commonly referred to as dAMP sodium, is a nucleotide that plays a crucial role in various biochemical processes, particularly in the synthesis of DNA. It is a derivative of adenosine, where the hydroxyl group at the 2' position of the ribose sugar is replaced by a hydrogen atom, resulting in a deoxyribose structure. The molecule consists of a purine base (adenine), a deoxyribose sugar, and a phosphate group attached to the 3' position of the sugar. The sodium salt form indicates that the phosphate group is ionically associated with sodium ions, which can enhance its solubility in aqueous solutions. dAMP is involved in cellular metabolism and is a building block for DNA synthesis, serving as a substrate for DNA polymerases during replication and repair processes. Additionally, it can participate in signaling pathways and is important in the regulation of various enzymatic activities. Its stability and reactivity are influenced by the presence of the phosphate group, making it a vital component in molecular biology and biochemistry.

Formula: C₁₀H₁₄N₅NaO₆P

InChI: InChI=1/C10H14N5O6P.Na/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(6(2-16)20-7)21-22(17,18)19;/h3-7,16H,1-2H2,(H2,11,12,13)(H2,17,18,19);

SMILES: C1C(C(CO)OC1n1cnc2c(N)ncnc12)OP(=O)(O)O.[Na]

Synonyms:

• 9H-purin-6-amine, 9-(2-deoxy-3-O-phosphonopentofuranosyl)-, monosodium salt

2''-Deoxyadenosine 3''-monophosphate sodium salt

CAS: 102832-10-0

Ref: 7W-GN1373

2'-Deoxyadenosine-3'-monophosphate sodium salt

CAS: 102832-10-0

2'-Deoxyadenosine-3'-monophosphate sodium salt (dAMP) is a novel nucleoside analog that is the sodium salt of 2'-deoxyadenosine-3'-monophosphate. It has shown anticancer and antiviral activity in vitro, as well as cytotoxicity against some human cancer cell lines. It has also been shown to be active against HIV-1 and herpes simplex virus type 1. The drug is modified with an amino group at the 2' position of the ribose sugar, which increases its stability in vivo and reduces its toxicity. This product also contains high purity, high quality, and novel deoxyribonucleosides that are synthesized by a phosphoramidite method.

Formula: C₁₀H₁₄N₅O₆P·2Na

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 377.2 g/mol

Ref: 3D-ND05758

2'-Deoxyadenosine-3'-monophosphate xSodium Salt

CAS: 102832-10-0

Applications 2'-Deoxyadenosine-3'-monophosphate sodium salt (CAS# 102832-10-0) is a useful research chemical compound.

Formula: C₁₀H₁₄N₅O₆P•xNa

Color and Shape: White To Off-White

Molecular weight: 377.2

Ref: TR-D211920