CAS 102932-25-2

7-HYDROXY DOXAZOSIN

Description:

7-Hydroxy doxazosin is a chemical compound that belongs to the class of quinazoline derivatives, primarily known for its role as an alpha-1 adrenergic antagonist. It is a metabolite of doxazosin, which is commonly used in the treatment of hypertension and benign prostatic hyperplasia. The presence of a hydroxyl group at the 7-position of the quinazoline ring enhances its pharmacological properties. This compound exhibits a mechanism of action that involves the selective blockade of alpha-1 adrenergic receptors, leading to vasodilation and a reduction in blood pressure. Additionally, 7-hydroxy doxazosin may have implications in research related to cardiovascular health and prostate conditions. Its chemical structure contributes to its solubility and bioavailability, making it an important subject of study in medicinal chemistry. As with many pharmaceutical compounds, understanding its pharmacokinetics, metabolism, and potential side effects is crucial for its therapeutic application.

Formula: C₂₂H₂₃N₅O₅

InChI: InChI=1/C22H23N5O5/c1-30-18-10-13-14(11-15(18)28)24-22(25-20(13)23)27-8-6-26(7-9-27)21(29)19-12-31-16-4-2-3-5-17(16)32-19/h2-5,10-11,19,28H,6-9,12H2,1H3,(H2,23,24,25)

SMILES: COc1cc2c(cc1O)nc([nH]c2=N)N1CCN(CC1)C(=O)C1COc2ccccc2O1

Synonyms:

• 1-(4-Amino-7-hydroxy-2-methoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl-piperazine

7-Hydroxy Doxazosin

Controlled Product

CAS: 102932-25-2

Formula: C₂₂H₂₃N₅O₅

Color and Shape: Neat

Molecular weight: 437.45

Ref: TR-H941775

7-Hydroxy Doxazosin

CAS: 102932-25-2

Formula: C₂₂H₂₃N₅O₅

Molecular weight: 437.46

Ref: ST-EA-CP-D26019

7-Hydroxy doxazosin

CAS: 102932-25-2

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Formula: C₂₂H₂₃N₅O₅

Purity: Min. 95%

Molecular weight: 437.45 g/mol

Ref: 3D-FH23987