CAS 102932-29-6
:6'-HYDROXY DOXAZOSIN
Description:
6'-Hydroxy doxazosin is a chemical compound that belongs to the class of quinazoline derivatives, primarily known for its application as an antihypertensive and alpha-1 adrenergic antagonist. This compound is characterized by the presence of a hydroxyl group at the 6' position of the doxazosin structure, which may influence its pharmacological properties and metabolic pathways. It typically exhibits a moderate to high solubility in organic solvents and may have varying solubility in water, depending on the pH and other conditions. The molecular structure of 6'-hydroxy doxazosin contributes to its biological activity, particularly in the modulation of vascular smooth muscle contraction and its potential use in treating conditions like hypertension and benign prostatic hyperplasia. Additionally, the compound's stability, reactivity, and interaction with biological targets are influenced by its functional groups and overall molecular conformation. As with many pharmaceutical compounds, safety and efficacy profiles are critical for its therapeutic applications.
Formula:C23H25N5O6
InChI:InChI=1/C23H25N5O6/c1-31-17-10-14-15(11-18(17)32-2)25-23(26-21(14)24)28-7-5-27(6-8-28)22(30)20-12-33-16-4-3-13(29)9-19(16)34-20/h3-4,9-11,20,29H,5-8,12H2,1-2H3,(H2,24,25,26)
SMILES:COc1cc2c(cc1OC)nc([nH]c2=N)N1CCN(CC1)C(=O)C1COc2ccc(cc2O1)O
Synonyms:- 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-6-hydroxy-1,4-benzodioxin-2-yl)carbonyl-piperazine
- [4-(4-Amino-6,7-Dimethoxyquinazolin-2-Yl)Piperazin-1-Yl](7-Hydroxy-2,3-Dihydro-1,4-Benzodioxin-2-Yl)Methanone
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Found 4 products.
6'-Hydroxy doxazosin
CAS:<p>6'-Hydroxy doxazosin is a drug that belongs to the group of alpha-blockers. It is a potent inhibitor of lipoprotein oxidation, which may contribute to its antiplatelet and hypotensive activities. The effects of 6'-hydroxy doxazosin on cholesterol metabolism are not yet known. Although the drug has been shown to be effective in vivo, it has not been studied in humans.</p>Formula:C23H25N5O6Purity:Min. 95%Molecular weight:467.47 g/mol
