CAS 1029692-15-6

1-Methylethyl N-[(2S)-7-cyano-1,2,3,4-tetrahydro-4-(2-pyridinylmethyl)cyclopent[b]indol-2-yl]carbamate

Description:

1-Methylethyl N-[(2S)-7-cyano-1,2,3,4-tetrahydro-4-(2-pyridinylmethyl)cyclopent[b]indol-2-yl]carbamate, with CAS number 1029692-15-6, is a chemical compound that belongs to the class of carbamates. This substance features a complex structure characterized by a tetrahydroindole framework, which is fused with a pyridine moiety, contributing to its potential biological activity. The presence of a cyano group indicates possible reactivity and interaction with biological targets. The methylethyl group suggests that the compound may exhibit lipophilic properties, potentially influencing its solubility and permeability in biological systems. Such characteristics may render it of interest in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific pathways or receptors. Additionally, the stereochemistry indicated by the (2S) configuration suggests that the compound may exhibit chirality, which can significantly affect its pharmacodynamics and pharmacokinetics. Overall, this compound's unique structural features may contribute to its potential therapeutic applications.

Formula: C₂₂H₂₂N₄O₂

InChI: InChI=1S/C22H22N4O2/c1-14(2)28-22(27)25-17-10-19-18-9-15(12-23)6-7-20(18)26(21(19)11-17)13-16-5-3-4-8-24-16/h3-9,14,17H,10-11,13H2,1-2H3,(H,25,27)/t17-/m0/s1

InChI key: InChIKey=IHIWYQYVBNODSV-KRWDZBQOSA-N

SMILES: C(N1C2=C(C=3C1=CC=C(C#N)C3)C[C@H](NC(OC(C)C)=O)C2)C4=CC=CC=N4

Synonyms:

• Carbamic acid, N-[(2S)-7-cyano-1,2,3,4-tetrahydro-4-(2-pyridinylmethyl)cyclopent[b]indol-2-yl]-, 1-methylethyl ester
• 1-Methylethyl N-[(2S)-7-cyano-1,2,3,4-tetrahydro-4-(2-pyridinylmethyl)cyclopent[b]indol-2-yl]carbamate
• LY 2452473
• (S)-[7-Cyano-4-[(pyridin-2-yl)methyl]-1,2,3,4-tetrahydrocyclopenta[b]indol-2-yl]carbamic acid isopropyl ester
• TT 701
• Isopropyl (2S)-7-Cyano-4-(pyridin-2-ylmethyl)-1,2,3,4-tetrah
• (S)-ISOPROPYL (7-CYANO-4-(PYRIDIN-2-YLMETHYL)-1,2,3,4-TETRAHYDROCYCLOPENTA[B]INDOL-2-YL)CARBAMATE
• LY-2452473,LY2452473
• Isopropyl (2S)-7-Cyano-4-(pyridin-2-ylmethyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-2-ylcarbama
• propan-2-yl N-[(2S)-7-cyano-4-(pyridin-2-ylmethyl)-2,3-dihydro-1H-cyclopenta[b]indol-2-yl]carbamate
• Isopropyl (2S)-7-Cyano-4-(pyridin-2-ylmethyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-2-ylcarbamate

LY2452473

CAS: 1029692-15-6

LY2452473

Purity: ≥98%

Molecular weight: 374.44g/mol

Ref: 54-BUP08654

LY 2452473

CAS: 1029692-15-6

Formula: C₂₂H₂₂N₄O₂

Molecular weight: 374.44

Ref: 4Z-L-194001

LY2452473

CAS: 1029692-15-6

LY2452473 (OPK 88004) is an orally available and selective androgen receptor modulator with potential anticancer activity for the study of prostate cancer.

Formula: C₂₂H₂₂N₄O₂

Purity: 99.72%

Color and Shape: Solid

Molecular weight: 374.44

Ref: TM-T15804

Isopropyl (2S)-7-Cyano-4-(pyridin-2-ylmethyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-2-ylcarbamate

Controlled Product

CAS: 1029692-15-6

Applications Isopropyl (2S)-7-Cyano-4-(pyridin-2-ylmethyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-2-ylcarbamate (CAS# 1029692-15-6) is a useful research chemical compound.

Formula: C₂₂H₂₂N₄O₂

Color and Shape: Off-White

Molecular weight: 374.44

Ref: TR-I065705

LY24522473

CAS: 1029692-15-6

LY24522473 is a potent and selective CDK4/6 inhibitor that blocks the catalytic activity of these enzymes. It has been shown to inhibit phosphodiesterase type-5 (PDE5), which is responsible for degradation of cyclic guanosine monophosphate (cGMP), and was used in patients with cancer. LY24522473 also inhibits the estrogen receptor modulators, leading to suppression of tumor growth in animal models. The drug has been found to have anti-inflammatory effects by reducing matrix metalloproteinases and inflammatory cytokines, such as TNF-α, IL-1β, IL-6, IL-8, and IL-10. LY24522473 can be administered orally in tablet form at a neutral pH.

Formula: C₂₂H₂₂N₄O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 374.44 g/mol

Ref: 3D-FL167406