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CAS 102978-36-9

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2,3-dihydro-5-fluorotryptophan

Description:
2,3-Dihydro-5-fluorotryptophan is an analog of the amino acid tryptophan, characterized by the presence of a fluorine atom at the 5-position of the indole ring and a saturated (dihydro) structure at the 2 and 3 positions. This modification can influence its biochemical properties, including its interaction with enzymes and receptors. The fluorine substitution may enhance lipophilicity, potentially affecting its absorption and distribution in biological systems. As a tryptophan derivative, it may participate in various metabolic pathways, including serotonin synthesis, and could have implications in neuropharmacology and medicinal chemistry. The compound is of interest in research for its potential roles in drug development, particularly in the context of neuroactive compounds. Its unique structure may also provide insights into structure-activity relationships in related compounds. Safety and handling considerations should be observed, as with any chemical substance, particularly in laboratory settings.
Formula:C11H13FN2O2
InChI:InChI=1/C11H13FN2O2/c12-7-1-2-10-8(4-7)6(5-14-10)3-9(13)11(15)16/h1-2,4,6,9,14H,3,5,13H2,(H,15,16)/t6-,9-/m0/s1
SMILES:c1cc2c(cc1F)[C@@H](C[C@@H](C(=O)O)N)CN2
Synonyms:
  • 2,3-Dihydro-5-fluoro-L-tryptophan
  • 3-[(3R)-5-fluoro-2,3-dihydro-1H-indol-3-yl]-L-alanine
  • 2,3-Dihydro-5-fluorotryptophan
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