CAS 10299-44-2
:8-Azaadenosine
Description:
8-Azaadenosine, with the CAS number 10299-44-2, is a modified nucleoside that features an azole ring in place of the nitrogen atom at the 8-position of adenine. This structural alteration imparts unique biochemical properties to the molecule, influencing its role in various biological processes. It is known to exhibit antiviral and anticancer activities, making it of interest in pharmaceutical research. The compound is soluble in water and polar solvents, which facilitates its use in biological assays. Additionally, 8-Azaadenosine can participate in nucleic acid metabolism and may act as a substrate for certain enzymes, impacting cellular signaling pathways. Its ability to mimic natural nucleosides allows it to interact with nucleic acid structures, potentially influencing gene expression and cellular functions. Overall, 8-Azaadenosine serves as a valuable tool in molecular biology and medicinal chemistry, contributing to the understanding of nucleoside function and the development of therapeutic agents.
Formula:C9H12N6O4
InChI:InChI=1S/C9H12N6O4/c10-7-4-8(12-2-11-7)15(14-13-4)9-6(18)5(17)3(1-16)19-9/h2-3,5-6,9,16-18H,1H2,(H2,10,11,12)/t3-,5-,6-,9-/m1/s1
InChI key:InChIKey=OAUKGFJQZRGECT-UUOKFMHZSA-N
SMILES:O[C@H]1[C@H](N2C=3C(N=N2)=C(N)N=CN3)O[C@H](CO)[C@H]1O
Synonyms:- 3-Beta-D-Ribofuranosyl-3H-1,2,3-Triazolo(4,5-D)Pyrimidin-7-Amine
- 3-Triazolo(4,5-D)Pyrimidin-7-Amine,3-Beta-D-Ribofuranosyl-3H-2
- 3-pentofuranosyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine
- 3-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine
- 3H-1,2,3-Triazolo[4,5-d]pyrimidin-7-amine, 3-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
- 3H-v-Triazolo[4,5-d]pyrimidine, 7-amino-3-beta.-D-ribofuranosyl-
- 3H-v-Triazolo[4,5-d]pyrimidine, 7-amino-3-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
- 5-D)Pyrimidine,7-Amino-3-Beta-D-Ribofuranosyl-3H-V-Triazolo(
- 7-Amino-3-β-<span class="text-smallcaps">D</span>-ribofuranosyl-v-triazolo[4,5-d]pyrimidine
- NSC 72961
- 7-Amino-3-β-D-ribofuranosyl-v-triazolo[4,5-d]pyrimidine
- 3-β-D-Ribofuranosyl-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine
- 3H-v-Triazolo[4,5-d]pyrimidine, 7-amino-3-β-D-ribofuranosyl-
- 3H-1,2,3-Triazolo[4,5-d]pyrimidin-7-amine, 3-β-D-ribofuranosyl-
- See more synonyms
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Found 8 products.
8-Azaadenosine
CAS:Formula:C9H12N6O4Purity:≥ 97.0%Color and Shape:White to off-white solidMolecular weight:268.238-Azaadenosine
CAS:<p>8-Azaadenosine inhibits ADAR1, blocks RNA editing, and reduces thyroid cancer cell proliferation and spread.</p>Formula:C9H12N6O4Purity:99.39%Color and Shape:SolidMolecular weight:268.238-Azaadenosine
CAS:Controlled Product<p>Applications Hydrogen bonding in 8-Azaadenosine was examined in this study.8-Azaadenosine is one of the best substrates of highly purified rabbit liver adenosine kinase.<br>References Jeffrey, G., et al.: Int. J. Biol. Macromol., 7, 336 (1985).Miller, R., et al.: J. Biol. Chem., 254, 2346 (1979).<br></p>Formula:C9H12N6O4Color and Shape:NeatMolecular weight:268.238-Azaadenosine
CAS:<p>8-Azaadenosine is a purine nucleoside that is used as a template for DNA replication. The zwitterionic form of 8-Azaadenosine is found in plants and is converted to the charged form by enzymatic reactions. 8-Azaadenosine binds to the dna template strand and acts as a hydrogen bond donor, which stabilizes the transition state of the reaction and inhibits enzyme activity. This drug has been shown to affect polymerase chain reaction (PCR) by inhibiting DNA synthesis and it has been used in cancer cell lines with resistant mutants, such as Herpes simplex virus type 1 (HSV1).</p>Formula:C9H12N6O4Purity:Min. 97 Area-%Color and Shape:Off-White PowderMolecular weight:268.23 g/mol
