Description:(D-Ser4)-Triptorelin, with the CAS number 102992-39-2, is a synthetic peptide and a derivative of gonadotropin-releasing hormone (GnRH). It is characterized by its ability to modulate the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland, thereby influencing reproductive hormone levels. This compound is typically utilized in medical applications, particularly in the treatment of hormone-sensitive conditions such as prostate cancer and endometriosis. The structure of (D-Ser4)-Triptorelin includes a modified amino acid sequence that enhances its stability and potency compared to natural GnRH. It is administered via injection and has a prolonged half-life, allowing for less frequent dosing. The peptide exhibits high specificity for GnRH receptors, making it effective in downregulating gonadal hormone production. As with many peptides, its pharmacological effects are closely tied to its molecular structure, which dictates its interaction with biological systems. Safety and efficacy profiles are established through clinical studies, guiding its therapeutic use.
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