CAS 103-16-2

Monobenzone

Description:

Monobenzone, also known as monobenzyl ether of hydroquinone, is an organic compound with the chemical formula C13H12O2. It is primarily recognized for its use in dermatological applications, particularly as a depigmenting agent in the treatment of skin conditions such as vitiligo. Monobenzone functions by inhibiting the activity of the enzyme tyrosinase, which is crucial for melanin production in melanocytes, leading to a reduction in skin pigmentation. The substance appears as a white to off-white crystalline powder and is typically insoluble in water but soluble in organic solvents like ethanol and acetone. Its stability is influenced by light and heat, necessitating careful storage conditions. While it is effective for its intended use, monobenzone can cause side effects, including skin irritation and increased sensitivity to sunlight. Due to its potent effects on skin pigmentation, its use is often regulated, and it is essential for users to follow medical guidance when using products containing this compound.

Formula: C₁₃H₁₂O₂

InChI: InChI=1S/C13H12O2/c14-12-6-8-13(9-7-12)15-10-11-4-2-1-3-5-11/h1-9,14H,10H2

InChI key: InChIKey=VYQNWZOUAUKGHI-UHFFFAOYSA-N

SMILES: O(CC1=CC=CC=C1)C2=CC=C(O)C=C2

Synonyms:

• 4-(Phenylmethoxy)phenol
• 4-Benzyloxy Phenol
• 4-Benzyloxyphenol
• 4-benzyloxy phenol (Monobenzone)
• Agerite
• Agerite alba
• Alba-Dome
• Benoquin
• Benzoquin
• Benzyl hydroquinone
• Benzyl p-hydroxyphenyl ether
• Carmifal
• Depigman
• Dermochinona
• Hydrochinon-Benzylaether
• Hydroquinone benzyl ether
• Leucodinine
• Monobenzon
• Monobenzona
• Monobenzone
• Monobenzyl ether hydroquinone
• Monobenzyl hydroquinone
• Nsc 2132
• Nsc 33918
• PBP
• Phenol, p-(benzyloxy)-
• Phenol,4-(Phenylmethoxy)-
• Pigmex
• Superlite
• Superlite (antioxidant)
• p-(Benzyloxy)phenol

4-(Benzyloxy)phenol

CAS: 103-16-2

Formula: C₁₃H₁₂O₂

Purity: >99.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 200.24

Ref: 3B-B1104

4-Benzyloxyphenol, 98+%

CAS: 103-16-2

4-Benzyloxyphenol is used in the synthesis of bis(4-benzyloxyphenoxy)phenyl phosphine oxide. It plays an essential role in the preparation of hetaryl-azophenol dyes via heterocyclic amines in nitrosyl sulphuric acid. It is also used for polyester fiber dyeing and in rubber industry. It acts as a dep

Formula: C₁₃H₁₂O₂

Purity: 98+%

Color and Shape: White to cream to pale brown to pale gray, Crystals or powder or crystalline powder

Molecular weight: 200.24

Ref: 02-A14843

Monobenzone

CAS: 103-16-2

Ether-phenols, ether-alcohol-phenols and their halogena

Formula: C₁₃H₁₂O₂

Color and Shape: White Powder

Molecular weight: 200.23 g/mol

Ref: 45-1445506

Monobenzone

CAS: 103-16-2

Monobenzone (Benoquin) is a Depigmenting Agent.

Formula: C₁₃H₁₂O₂

Purity: 99.87%

Color and Shape: Lustrous Leaflets From Water Solid

Molecular weight: 200.23

Ref: TM-T0759

4-Benzyloxyphenol

CAS: 103-16-2

Formula: C₁₃H₁₂O₂

Purity: 96%

Color and Shape: Solid

Molecular weight: 200.2332

Ref: IN-DA003KTR

4-(Benzyloxy)phenol

CAS: 103-16-2

Formula: C₁₃H₁₂O₂

Purity: ≥ 98.0%

Color and Shape: White, off-white or pale yellow-brown powder or crystals

Molecular weight: 200.24

Ref: 7W-GP9986

Monobenzone

CAS: 103-16-2

Monobenzone

Purity: ≥98%

Molecular weight: 200.23g/mol

Ref: 54-BUP19189

4-(Benzyloxy)phenol

Controlled Product

CAS: 103-16-2

Formula: C₁₃H₁₂O₂

Color and Shape: Neat

Molecular weight: 200.23

Ref: 04-C10572800

4-(Benzyloxy)phenol

CAS: 103-16-2

4-(Benzyloxy)phenol

Formula: C₁₃H₁₂O₂

Purity: 98%

Color and Shape: white crystalline powder

Molecular weight: 200.23g/mol

Ref: 54-OR4376

4-(Benzyloxy)phenol

Controlled Product

CAS: 103-16-2

Applications 4-(Benzyloxy)phenol is topically used by patients with extensive vitiligo to depigment their remaining normally pigmented skin.
References Hedges, T.R.3rd., et. al.: Arch. Ophthalmol-chic., 101, 64 (1983)

Formula: C₁₃H₁₂O₂

Color and Shape: Neat

Molecular weight: 200.23

Ref: TR-B288190

Hydroquinone monobenzyl ether

CAS: 103-16-2

Hydroquinone monobenzyl ether (MBEH) is a reactive chemical that has been used as a pharmacological treatment for cancer. It reacts with DNA to form a covalent bond, which inhibits the process of transcription and replication. MBEH has been shown to be effective in treating bowel disease and skin cancer. MBEH also has an effect on autoimmune diseases and infectious diseases because it blocks the production of inflammatory mediators such as prostaglandins, leukotrienes, and cytokines. MBEH is converted to monobenzone (MBZ) by cytochrome P450 enzymes, which inhibits DNA synthesis by binding to the enzyme RNA polymerase.

Formula: C₁₃H₁₂O₂

Color and Shape: Powder

Molecular weight: 200.23 g/mol

Ref: 3D-FH02681

4-Benzyloxyphenol

CAS: 103-16-2

Formula: C₁₃H₁₂O₂

Purity: 96%

Color and Shape: White to very pale yellow powder

Molecular weight: 200.237

Ref: 10-F078490

Monobenzone

CAS: 103-16-2

Monobenzone is a skin-lightening agent that belongs to the group of dithiocarbamates. It is used as a topical medication for the treatment of skin diseases such as vitiligo and acne. Monobenzone inhibits tyrosinase, an enzyme involved in melanin synthesis, by binding to its active site. This compound also has been shown to have chemotherapeutic activity against cancer tissues and infectious diseases. Monobenzone is used in analytical methods to determine the presence of melanoma antigen in blood plasma and other body fluids. Monobenzone reacts with potassium dichromate to form a red-orange precipitate, which can be measured spectrophotometrically at 590 nm.

Formula: C₁₃H₁₂O₂

Purity: Min. 95%

Molecular weight: 200.23 g/mol

Ref: 3D-FH178558