CAS 10300-22-8

3'-O-Methyl-D-adenosine

Description:

3'-O-Methyl-D-adenosine is a modified nucleoside derived from adenosine, characterized by the presence of a methoxy group at the 3' position of the ribose sugar. This modification can influence the biological activity and stability of the molecule, making it relevant in various biochemical contexts, particularly in RNA metabolism and signaling pathways. The compound is often studied for its role in cellular processes, including its potential effects on gene expression and its involvement in the regulation of cellular functions. In terms of solubility, 3'-O-Methyl-D-adenosine is typically soluble in polar solvents, which is common for nucleosides. Its molecular structure includes a purine base (adenine) linked to a ribose sugar, contributing to its classification as a nucleoside. The presence of the methoxy group can also affect its interaction with enzymes and receptors, making it a subject of interest in pharmacological research. Overall, 3'-O-Methyl-D-adenosine serves as an important tool in molecular biology and biochemistry for studying nucleic acid modifications and their implications in cellular processes.

Formula: C₁₁H₁₅N₅O₄

InChI: InChI=1/C11H15N5O4/c1-19-8-5(2-17)20-11(7(8)18)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17-18H,2H2,1H3,(H2,12,13,14)

InChI key: InChIKey=RYAFZRROCNNRFK-IOSLPCCCSA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CO)[C@H]1OC

Synonyms:

• 3'-O-Methyl-Adenosine
• 3'-O-Methyladenosine
• 9-(3-O-methylpentofuranosyl)-9H-purin-6-amine
• Adenosine, 3'-O-methyl- (8CI)(9CI)
• Adenosine, 3′-O-methyl-
• Nsc 103062
• -Bi-p-acetanisidide
• -Hydroxyethyl)diosmin
• -Hydroxypuerarin
• -Amino-N6-benzoyl-2'
• 5-Dimethoxy-2,4'
• -Tri-O-acetylcytidine HCI
• -Sialyl Lewis X- biotin
• 2-Methyl-3-(2'
• -chloro-4a'
• 6-Chloro-7-deaza-9-(5'
• -didehydroinosine
• -Dideoxyuridine-5'
• -Dehydro-5'
• -pentalen]-5'
• 2H7
• -diyl)-a-D-mannopyanoside
• 5-Chloro-2'
• Biotin-11-deoxyuridine-5'
• NT5C (5'
• -Anhydroinosine
• -O-Acetylthymidine
• -desoxyuridine
• 15N4]-L-Arginine HCl
• 9-(5'
• -dinitro-1,1'
• -Tetrabenzoyladenosine
• -Sulpho Lewis a (BSA)
• H)-isoquinolin]-6'
• -Des(dimethylamino)-3'
• -didehydroadenosine
• -yl)-cytosine
• -hydroxyl-kinase) (FITC)
• -deoxy-uridine-5&lsquo
• -O-(1-thiotriphosphate)
• -hydroxyl-kinase) (APC)
• 8'
• aS-(3'
• -phosphodiesterase) (HRP)
• -Dideoxyinosine-5'
• 15N]-L-Proline
• -tri-O-Acetylguanosine &ge
• -hydroxyl-kinase) (PE)
• -Sialyl-3-fucosyllactose-BSA
• 2-Hydroxy-2-(6'
• -tetrahydro-2'
• -biphenyl]-2-yl)acetamide
• -deoxythymidine-d3)
• -O-Allyladenosine
• -dideoxy-guanosine
• -Dideoxy-3'
• 5-Formyl-2'
• -Sialyl Lewis A-PAA-Biotin
• -Chloro-2-bromopropiophenone
• -tri-O-acetylinosine
• (-)-Carbovir-5&rsquo
• -(5-Fluorescein)-CPG
• H-spiro[[1,3]dioxane-2,2'
• 5-Chloro-3'
• -(dimethylamino)-5'
• -tri-O-Acetyluridine &ge
• CNPase (CNP, 2'
• -Azido-N6-benzoyl-2'
• -Dideoxyinosine 99+% (HPLC)
• -O-Acetylthymidine 99+%
• Exoribonuclease 1)
• -oxo-3'
• -Azido-3'
• -Dihydro-1'
• Azidothymidine (3'
• H)-dione-d5
• -Azido-N4-benzoyl-2'
• -Sialyl Lewis X-PAA-Biotin
• -O-DMT-cytidine
• 3'-O-Methyl-D-adenosine
• -O-tosyladenosine
• CNP (2'
• -[1H]phenalen]-3-one
• -fluoro-alpha-uridine
• -deoxy-5-fluorocytidine &ge
• -Deoxyadenosine CPG
• -Anhydroadenosine
• -fluoroacetophone
• -Hydroxy simvastatin
• ), Endonuclease G-Like)
• -Amino-N4-benzoyl-2'
• -Hydroxy-5,7,4'
• -Des(hydroxymethyl)-5'
• -Acetyl-4'
• N4-Acetyl-1-(2'
• -O-Methyluridine-5'
• -p-Hydroxy paclitaxel
• Phenyl 3,4-O-(2'
• 5-Chloro-5'
• -O-DMT-thymidine 5'
• -Bi-p-acetanisidide-d6
• -Tri-O-benzoyluridine
• -deoxythymidine methyl-D3
• -Dideoxyadenosine-5'
• 6-Amino-9-(2'
• -dideoxy-7-iodoadenosine
• -O-Propargylcytidine
• -Dideoxythymidine &ge
• -Azido-1'
• -kinase/3'
• -Trichlorosalicylanilide
• -Amino-3'
• uridine 2'
• Iminobis-propanamide
• -(hydroxymethyl)-5'
• -Epi gemcitabine
• -Trifluoromethyl Cinacalcet
• -Deoxyadenosine-1'
• CNP, ID (2'
• -didehydro-5'
• -dihydro-4'
• -Deoxy-N6-lauroyladenosine
• Tetra-​
• -phosphodiesterase) (AP)
• -phosphodiesterase) (PE)
• -dimethoxybutane-2'
• -N-formyl azithromycin
• -thia-cytidine-5'
• -Tri-O-benzoylguanosine
• -Methyl-[1,1'
• 3'-OMe-A
• -dihydroxypropyl)quinoxaline
• -Tri-O-acetyl-6-azauridine
• -Hydroxyquinophthalone
• -Dideoxyuridine 99+% (HPLC)
• stilbenequinone
• XRN1 (5'
• -dipropanoic Acid 3,3'
• -Triacetyl-azacytidine &ge
• -Sialyllactose-sp-biotin
• &rarr
• -13C5 Monohydrate
• -Bromo-5'
• -h]quinoxaline
• Tiphenylphosphine-3,3'
• -Di-O-acetyl-D-uridine
• -N-ethylcarboxamide-2'
• -Destrifluoromethyl 2'
• 2-Iodo-2'
• -O-DMT-thymidine
• -Iodo-4'
• -Ethyl-7'
• -Sialyl Lewis A-sp-biotin
• -O-DMT-uridine 2'
• -Methoxyflavonol
• -Fluoro-[1,1'
• -O-Methyladenosine 5'
• -Deoxy-5-chlorocytidine)
• Acyclovir 5'
• -O-Propargylguanosine
• -Didehydro-3'
• -Sulfated Lewis X
• -Bromoacetophenone &ge
• -deoxythymidine 5'
• 4-Cyano-3,3'
• -Deoxy-5-chlorouridine)
• -deoxyuridine (2'
• 15N2]-L-Glutamine
• -hydroxyl-kinase)
• -cyclic-nucleotide 3'
• -Dibenzyloxy-&alpha
• -fluoro-a-uridine
• -Sulpho Lewis x (BSA)
• -deoxy-5-fluorocytidine
• -Azido-5'
• 3'-O-Me-Ar
• -Apo-b-carotenal
• 5-Fluoro-3'
• -oxathiolan-5'
• Capecitabine-2'
• N-Benzyl biotin
• -Sulfated Lewis A
• -keto azithromycin
• -phosphodiesterase, CNPase)
• -iodothymidine
• -O-benzoyl-3'
• 7-Di-O-methyl quercetin
• 7-Iodo-2'
• -Azido-N4-benzoyl-5'
• -indolizin]-7'
• -Deoxy-N6-propionyladenosine
• -Acetophenonecarboxylic acid
• -Deoxyinosine 2&rsquo
• CNPase (2'
• -phosphatase, DNA 5'
• -epi-Azido-3'
• -phosphodiesterase, CNP)
• -dideoxy-2-fluoroadenosine
• aR)-Hexahydro-5'
• -Dihydro-7'
• -methoxyflavanone
• -Didehydro-2'
• 3'
• -hi]xanthene-7,9-dione
• -O-Methylcytidine 5'
• Cytidine 2'
• -Difluoro-4'
• XRN2, NT (XRN2, 5'
• 6-D6)
• -(R)-Hydroxy-2'
• -p-Dihydroxy Paclitaxel
• -O-Methyl-D-adenosine
• -Tri-O-acetylisoguanosine
• -L-menthyloxycarbonyl-1'
• -O-Methyl-5-methylcytidine
• -Deoxy-5-methyluridine
• -Methoxypuerarin
• -iodo-2'
• -Isopropylidenecytidine
• N,N,2'
• -Tri-O-acetylnebularine
• -phosphodiesterase) (FITC)
• -methoxydiclofenac
• -O-tosyladenosine-13C5
• -dideoxy-2'
• (E)-2-Acetoxy-2'
• H)-furo[2,3-b]pyridine
• -Hydroxy warfarin
• -Deoxy-N6-octanoyladenosine
• S)-6,6'
• Adenosine Cyclic 2'
• -Benzyloxyphenylacetonitrile
• H)-naphthalene]-1'
• -O-Acetyl-2'
• H)-indolizine]-6'
• -N-Desmethyl-3'
• 2-Chloro-5'
• -dideoxy-5'
• Stavudine-d3 (2'
• -hydroxyl-kinase) (Biotin)
• -ol &ge
• -monothiophosphate
• -O-Benzoylthymidine
• 3S,&alpha
• -phosphatase, 2'
• Benzyl 3,4-O-(2'
• -Deoxyuridine-1'
• -nucleotidase, Cytosolic)
• -Sialyl-3-fucosyllactose
• -oxirane] Hydrochloride
• -Phenylboronate-5'
• -deoxy- cytidine-5&lsquo
• -(Phosphinidyne-&kappa
• XRN2 (5'
• 7,8,7'
• -Tri-O-benzylfucosyllactose
• -Methoxy-5'
• -hydroxy-7'
• -O-Isopropylidenecytidine
• 6-Disinapoylsucrose
• -bromo-inosine 2&rsquo
• -Dideoxy-5-iodouridine
• (Methyl-13C,d3)-​
• -phosphodiesterase) (APC)
• Iminobis-propanamide Sulfate
• -O-Isopropylideneinosine &ge
• -O-Isopropylidene-5'
• -[N-(HABA-CBz)] 3,5,6'
• -chlorothymidine
• Biotin-18-cytidine-5'
• -triphosphate ammonium salt
• -O-DMT-5-methyluridine 2'
• NT5M (5'
• Dipyrazino[2,3-f:2'
• Naphtho[1,8-gh]naphtho[1'
• -O-Allyluridine
• -Dideoxycytidine-5'
• -hydroxyl-kinase) (AP)
• -dimethoxybutan-2'
• -O-Methylguanosine 5'
• -O-Acetyl-5'
• -O-Acetyl ADP Ribose-d3)
• -Dideoxyguanosine-5'
• -dideoxyuridine
• N-(4'
• -Tetradehydroastaxanthin
• -hydroxy-[1,1'
• -cyclic Carbonate
• -13C5
• -Demethyl papaverine
• -biphenyl]-4-yl)-N'
• -L-Prolyladenosine-5'
• 5-(Hydroxymethyl)-2'
• R,5'
• -N,N-Di(desmethyl)-3'
• -O-Methyl Quercetin 3-O-&beta
• Brassicasterol-(2,2'
• -e][1,4]diazepin-6-one-d2
• -Sialyl Lewisx-HSA
• -dideoxy-5-bromouridine
• 3,4,4'
• -Sialyl Lewis X-sp-biotin
• -Bis(benzyl) Ester
• 15N]-L-Methionine
• -(TrifluoroMethyl)-[1,1'
• (Bromomethyl-13C,d2)-​
• -O-methyuridine
• NT5M, CT (5'
• -carboxymethyl Decitabine
• -Phosphate 5'
• -O-tritylthymidine
• -phosphodiesterase) (Biotin)
• -Epilutein
• -O-Allylcytidine
• N-Acetyl-2'
• -Dioctadecyl-3,3,3'
• -Dideoxy-5-methylcytidine
• -O-Methyl-d3 Quercetin
• -Benzyloxyacetophenone &ge
• -Isopropylidene ribavirin
• -O-isopropylideneuridine
• -Triacetyl -azacytidine
• -Dehydrolutein

3'-O-Methyladenosine

CAS: 10300-22-8

Formula: C₁₁H₁₅N₅O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 281.2679

Ref: IN-DA007YBE

3''-O-Methyladenosine

CAS: 10300-22-8

Ref: 7W-GN5700

3’-O-Methyladenosine

CAS: 10300-22-8

3’-O-Methyladenosine

Purity: ≥98%

Molecular weight: 281.27g/mol

Ref: 54-BUP06686

3'-O-Methyladenosine

CAS: 10300-22-8

3’-O-Methyladenosine is an antiviral compound with inhibitory activity against West Nile Virus and can be used for the treatment of viral infections.3’-O-

Formula: C₁₁H₁₅N₅O₄

Purity: 99.93%

Color and Shape: Solid

Molecular weight: 281.27

Ref: TM-TNU0060

3'-O-Methyladenosine

CAS: 10300-22-8

3'-O-Methyladenosine (3'OMeA) is a monomethylated adenosine that belongs to the group of nucleosides. It has been found to inhibit the activity of adenosine receptors, which are important for the regulation of blood pressure and central nervous system function. 3'OMeA also inhibits virus replication in human lymphocytes. 3'OMeA is synthesized by reaction with methylamine and purification by column chromatography. The molecule is a potential therapeutic target for HIV/AIDS, as it can be used as a specific agonist in order to block viral entry into cells.

Formula: C₁₁H₁₅N₅O₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 281.27 g/mol

Ref: 3D-NM03526

(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol

CAS: 10300-22-8

Purity: 97%

Molecular weight: 281.2720032

Ref: 10-F780084

3'-O-Methyladenosine-D3

Controlled Product

CAS: 10300-22-8

Formula: C₁₁D₃H₁₂N₅O₄

Color and Shape: Neat

Molecular weight: 284.286

Ref: TR-O211427

3'-O-Methyladenosine

Controlled Product

CAS: 10300-22-8

Formula: C₁₁H₁₅N₅O₄

Color and Shape: Neat

Molecular weight: 281.268

Ref: TR-O211425