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CAS 10303-95-4

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1,3-Diaminoadamantane

Description:
1,3-Diaminoadamantane, also known as memantine, is a chemical compound characterized by its adamantane structure, which consists of a diamond-like cage of carbon atoms. This compound features two amino groups (-NH2) attached to the first and third carbon atoms of the adamantane framework, contributing to its unique properties. It is a white crystalline solid that is soluble in water and exhibits basic characteristics due to the presence of amino groups. 1,3-Diaminoadamantane is primarily recognized for its application in the treatment of neurodegenerative diseases, particularly Alzheimer's disease, as it acts as an NMDA receptor antagonist, helping to regulate glutamate activity in the brain. The compound has a relatively low toxicity profile and is well-tolerated in therapeutic doses. Its pharmacological properties, along with its structural stability, make it a subject of interest in medicinal chemistry and neuroscience research. Additionally, its ability to cross the blood-brain barrier enhances its effectiveness in neurological applications.
Formula:C10H18N2
InChI:InChI=1S/C10H18N2/c11-9-2-7-1-8(4-9)5-10(12,3-7)6-9/h7-8H,1-6,11-12H2
InChI key:InChIKey=FOLJMFFBEKONJP-UHFFFAOYSA-N
SMILES:NC12CC3(N)CC(C1)CC(C2)C3
Synonyms:
  • 1,3-Diaminoadamantane
  • 4. 1,3-Diaminoadamantane
  • Tricyclo[3.3.1.13,7]decane-1,3-diamine
  • Tricyclo[3.3.1.1<sup>3,7</sup>]decane-1,3-diamine
  • Tricyclo[3.3.1.1~3,7~]Decane-1,3-Diamine
  • 1,3-Adamantanediamine
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