CAS 10304-39-9

8-(p-Toluenesulfonylamino)quinoline

Description:

8-(p-Toluenesulfonylamino)quinoline, identified by its CAS number 10304-39-9, is an organic compound that features a quinoline core substituted with a p-toluenesulfonylamino group. This compound typically exhibits a yellow to orange crystalline appearance and is known for its solubility in organic solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF), while being less soluble in water. The presence of the sulfonamide functional group contributes to its potential as a versatile building block in organic synthesis and medicinal chemistry. It may exhibit biological activity, making it of interest in pharmaceutical research, particularly in the development of compounds with antimicrobial or anticancer properties. The compound's structure allows for various chemical modifications, which can enhance its reactivity and selectivity in different chemical reactions. As with many organic compounds, handling should be done with care, following appropriate safety protocols to mitigate any potential hazards associated with its use.

Formula: C₁₆H₁₄N₂O₂S

InChI: InChI=1/C16H14N2O2S/c1-12-7-9-14(10-8-12)21(19,20)18-15-6-2-4-13-5-3-11-17-16(13)15/h2-11,18H,1H3

InChI key: InChIKey=ZSMKPYXVUIWTCT-UHFFFAOYSA-N

SMILES: N(S(=O)(=O)C1=CC=C(C)C=C1)C=2C3=C(C=CC2)C=CC=N3

Synonyms:

• 4-Methyl-N-(8-quinolinyl)benzenesulfonamide
• 4-Methyl-N-8-quinolinylbenzenesulfonamide
• 4-methyl-N-(quinolin-8-yl)benzenesulfonamide
• 8-(4-Tolylsulfonylamino)Quinoline
• 8-(p-Toluenesulfonylamino)quinoline
• 8-(p-Tolylsulfonamido)quinoline
• 8-(p-Tolylsulfonylamino)quinoline
• 8-p-Tosylaminoquinoline
• Benzenesulfonamide, 4-methyl-N-8-quinolinyl-
• N-(8-Quinolyl)Toluene-4-Sulfonamide
• N-8-Quinolyl-p-toluenesulfonamide
• NSC 87883
• p-Toluenesulfonamide, N-8-quinolyl-
• 4-methyl-N-(quinolin-8-yl)benzene-1-sulfonamide
• 8-(Tosylamino)quinoline 97%
• N-(8-Quinolinyl)-p-toluenesulfonamide
• N-(8-Quinolyl)-4-methylbenzenesulfonamide
• 4-methyl-N-quinolin-8-ylbenzenesulfonamide
• 8-(TOSYLAMINO)QUINOLINE
• 8-(p-ToluenesulfonylaMino)quinoline, 97%
• 8-(p-Toluenesulfonylamino)quinoline,97%
• N-(Quinoline-8-yl)-4-methylbenzenesulfonamide

4-methyl-N-(quinolin-8-yl)benzene-1-sulfonamide

CAS: 10304-39-9

Formula: C₁₆H₁₄N₂O₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 298.3596

Ref: IN-DA007Y6Q

8-(Tosylamino)Quinoline

CAS: 10304-39-9

8-(Tosylamino)Quinoline

Purity: 98%+

Molecular weight: 298.36g/mol

Ref: 54-OR1024929

8-(Tosylamino)quinoline

CAS: 10304-39-9

Purity: 98%

Molecular weight: 298.3599853515625

Ref: 10-F635349

8-(Tosylamino)quinoline

CAS: 10304-39-9

8-(Tosylamino)quinoline is a quinoline derivative that inhibits the production of tumor necrosis factor-α (TNF-α) and other inflammatory mediators. 8-(Tosylamino)quinoline has been shown to inhibit the proliferation of muscle cells, which may be due to its anti-inflammatory properties. This drug also suppresses genes that are involved in cell growth and signaling, such as suppressor genes. 8-(Tosylamino)quinoline binds copper ions, which prevents the formation of reactive oxygen species and blocks the activation of nuclear factor kappa beta (NFκB), which regulates immune responses. It also inhibits autophagy, a process by which cells destroy their own intracellular contents during periods of starvation or stress.

Formula: C₁₆H₁₄N₂O₂S

Purity: Min. 95%

Molecular weight: 298.36 g/mol

Ref: 3D-KAA30439