CAS 10308-13-1

(4aR,6S,9Z,20S)-2,3,4,4a,5,6-Hexahydro-14-hydroxy-17,18-dimethoxy-20H-6,20-methano-11,15-metheno-1H,8H-benzo[g]pyrido[2,1-d][1,5]oxaazacyclohexadecin-8-one

Description:

The chemical substance with the name "(4aR,6S,9Z,20S)-2,3,4,4a,5,6-Hexahydro-14-hydroxy-17,18-dimethoxy-20H-6,20-methano-11,15-metheno-1H,8H-benzo[g]pyrido[2,1-d][1,5]oxaazacyclohexadecin-8-one" and CAS number "10308-13-1" is a complex organic compound characterized by its intricate polycyclic structure, which includes multiple fused rings and functional groups. This compound features a hexahydro framework, indicating a saturated cyclic structure with several stereocenters, contributing to its specific three-dimensional arrangement. The presence of hydroxyl (-OH) and methoxy (-OCH3) groups suggests potential for hydrogen bonding and reactivity, influencing its solubility and biological activity. The compound's unique structural features may confer specific pharmacological properties, making it of interest in medicinal chemistry. Its stereochemistry, denoted by the specific configuration at various chiral centers, is crucial for understanding its interactions with biological targets. Overall, this substance exemplifies the complexity often found in natural products and synthetic derivatives, highlighting the importance of detailed structural characterization in the field of chemistry.

Formula: C₂₆H₂₉NO₅

InChI: InChI=1S/C26H29NO5/c1-30-24-14-19-20(15-25(24)31-2)22-13-18(12-17-5-3-4-10-27(17)22)32-26(29)9-7-16-6-8-23(28)21(19)11-16/h6-9,11,14-15,17-18,22,28H,3-5,10,12-13H2,1-2H3/b9-7-/t17-,18+,22+/m1/s1

InChI key: InChIKey=WCZWUYYJZVBKDZ-VMSBZHFZSA-N

SMILES: O(C)C=1C=C2C(C=3C=C(C=CC3O)/C=C\C(=O)O[C@@]4(C[C@@]2(N5[C@@](C4)(CCCC5)[H])[H])[H])=CC1OC

Synonyms:

• (10alpha,13Z)-2'-Hydroxy-4'',5''-dimethoxylythran-12-one
• 18H-6,20-methano-15,11-metheno-2H,6H-pyrido[1,2-b][6,2]benzoxaazacyclohexadecin-18-one, 1,3,4,20,21,21a-hexahydro-12-hydroxy-8,9-dimethoxy-, (6S,16Z,20S,21aR)-
• Vertine
• 20H-6,20-Methano-11,15-metheno-1H,8H-benzo[g]pyrido[2,1-d][1,5]oxaazacyclohexadecin-8-one, 2,3,4,4a,5,6-hexahydro-14-hydroxy-17,18-dimethoxy-, (4aR,6S,9Z,20S)-
• Cryogenine
• Lythran-12-one, 2′-hydroxy-4′′,5′′-dimethoxy-, (10α)-
• Cryogenine
• Vertine
• (4aR,6S,9Z,20S)-2,3,4,4a,5,6-Hexahydro-14-hydroxy-17,18-dimethoxy-20H-6,20-methano-11,15-metheno-1H,8H-benzo[g]pyrido[2,1-d][1,5]oxaazacyclohexadecin-8-one

Cryogenine

CAS: 10308-13-1

Cryogenine, from H. salicifolia, is an anti-inflammatory alkaloid, blocks prostaglandin synthetase, and alleviates rat arthritis.

Formula: C₂₆H₂₉NO₅

Color and Shape: Solid

Molecular weight: 435.52

Ref: TM-T38327

Cryogenine

CAS: 10308-13-1

Cryogenine is a peptide which acts as an inhibitor. It binds to the active site of protein kinase C, preventing it from phosphorylating other proteins and thereby inhibiting protein synthesis. Cryogenine has been used as a research tool to study protein interactions, activators, and ligands. The high purity of this product makes it suitable for life science research such as ion channels and antibodies.

Formula: C₂₆H₂₉NO₅

Purity: Min. 95%

Molecular weight: 435.5 g/mol

Ref: 3D-KAA30813