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CAS 103122-78-7

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renin inhibitory peptide, R-PEP-27

Description:
Renin inhibitory peptide, known as R-PEP-27, is a synthetic peptide that plays a role in the regulation of blood pressure by inhibiting the activity of renin, an enzyme involved in the renin-angiotensin-aldosterone system (RAAS). This peptide is characterized by its specific amino acid sequence, which allows it to bind to renin and prevent its action, thereby reducing the production of angiotensin II, a potent vasoconstrictor. R-PEP-27 has been studied for its potential therapeutic applications in treating hypertension and related cardiovascular diseases. Its molecular structure contributes to its stability and bioactivity, making it a subject of interest in pharmacological research. The CAS number 103122-78-7 uniquely identifies this compound, facilitating its recognition in scientific literature and databases. Overall, R-PEP-27 represents a promising avenue for developing antihypertensive agents, with ongoing research aimed at understanding its mechanisms and optimizing its efficacy.
Formula:C54H75N13O9
InChI:InChI=1/C54H75N13O9/c1-5-33(4)47(53(75)63-41(24-35-16-10-7-11-17-35)50(72)65-46(69)27-45(68)38(55)22-32(2)3)66-51(73)42(25-36-28-56-30-59-36)61-49(71)40(23-34-14-8-6-9-15-34)62-52(74)44-19-13-21-67(44)54(76)43(26-37-29-57-31-60-37)64-48(70)39-18-12-20-58-39/h6-11,14-17,28-33,36-45,47,58,68H,5,12-13,18-27,55H2,1-4H3,(H,61,71)(H,62,74)(H,63,75)(H,64,70)(H,66,73)(H,65,69,72)/t33-,36?,37?,38-,39-,40-,41-,42-,43-,44-,45?,47-/m0/s1
Synonyms:
  • (S-(R*,R*))-N-(3-Hydroxy-6-methyl-1-oxo-4-((N-(N-(1-(N-L-prolyl-L-histidyl)-L-prolyl)-L-phenylalanyl)-L-histidyl)amino)heptyl)-L-isoleucyl-L-phenylalaninamide
  • Prolyl-histidyl-prolyl-phenylalanyl-histidyl-statine-isoleucyl-phenylalaninamide
  • R-PEP 27
  • Renin inhibitory peptide, R-pep-27
  • L-prolyl-3-(4H-imidazol-4-yl)-L-alanyl-L-prolyl-L-phenylalanyl-3-(4H-imidazol-4-yl)-L-alanyl-L-isoleucyl-N-[(4S)-4-amino-3-hydroxy-6-methylheptanoyl]-L-phenylalaninamide
  • Pro-his-pro-phe-his-statine-ile-phe-NH2
  • L-Phenylalaninamide, N-(3-hydroxy-6-methyl-1-oxo-4-((N-(N-(1-(N-L-prolyl-L-histidyl)-L-prolyl)-L-phenylalanyl)-L-histidyl)amino)heptyl)-L-isoleucyl-, (S-(R*,R*))-
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Found 1 products.
  • R-PEP 27
    Targetmol
    + Info

    R-PEP 27

    CAS:
    R-PEP 27 is an inhibitor of potent renin, decreased plasma angiotensin II, and blood pressure in normal volunteers.
    Formula:C54H75N13O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1050.26

    Ref: TM-T26127