CAS 103201-78-1

(4S)-4-Cyclohexyl-L-proline

Description:

(4S)-4-Cyclohexyl-L-proline is a chiral amino acid derivative characterized by its cyclohexyl side chain attached to the proline backbone. This compound features a five-membered pyrrolidine ring, which is typical of proline, and the cyclohexyl group contributes to its hydrophobic properties. The stereochemistry at the 4-position is crucial, as it influences the compound's biological activity and interaction with receptors or enzymes. (4S)-4-Cyclohexyl-L-proline is often studied in the context of peptide synthesis and drug design due to its potential to serve as a building block for bioactive compounds. Its unique structure may enhance the stability and selectivity of peptides, making it of interest in medicinal chemistry. Additionally, the presence of the cyclohexyl group can affect the conformational flexibility of the molecule, which is important for its function in biological systems. Overall, this compound exemplifies the significance of stereochemistry and structural features in the development of pharmaceuticals and therapeutic agents.

Formula: C₁₁H₁₉NO₂

InChI: InChI=1S/C11H19NO2/c13-11(14)10-6-9(7-12-10)8-4-2-1-3-5-8/h8-10,12H,1-7H2,(H,13,14)/t9-,10+/m1/s1

InChI key: InChIKey=XRZWVSXEDRYQGC-ZJUUUORDSA-N

SMILES: C(O)(=O)[C@@H]1C[C@H](CN1)[C@@H]2CCCCC2

Synonyms:

• (4S)-4-Cyclohexyl-<span class="text-smallcaps">L</span>-proline
• (4S)-4-cyclohexyl-L-proline
• <span class="text-smallcaps">L</span>-Proline, 4-cyclohexyl-, (4S)-
• <span class="text-smallcaps">L</span>-Proline, 4-cyclohexyl-, trans-
• Fosinopril Intermediate
• Trans-1-cyclohexy-L-proline
• L-Proline, 4-cyclohexyl-, (4S)-
• L-Proline, 4-cyclohexyl-, trans-
• (2S,4S)-4-Cyclohexylpyrrolidine-2-carboxylic acid

trans-4-Cyclohexyl-L-proline

CAS: 103201-78-1

Formula: C₁₁H₁₉NO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 197.2741

Ref: IN-DA00389R

Trans-4-Cyclohexyl-L-Proline

CAS: 103201-78-1

Trans-4-Cyclohexyl-L-Proline

Purity: 97%

Molecular weight: 197.27g/mol

Ref: 54-OR1015286

trans-4-Cyclohexyl-L-proline

CAS: 103201-78-1

Formula: C₁₁H₁₉NO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 197.278

Ref: 10-F078699

trans-4-Cyclohexyl-L-proline

CAS: 103201-78-1

Trans-4-Cyclohexyl-L-proline is an enolate that is used as a pharmaceutical intermediate. It has been shown to be effective in the synthesis of fosinopril sodium, a drug used for the treatment of hypertension and heart failure. Trans-4-Cyclohexyl-L-proline also has shown potential use as an antimicrobial agent. It can act as a nucleophilic agent, reacting with chloride ions to form an alkylating agent. The chlorinated product can undergo hydrolysis by hydrochloric acid to yield c1-4 alkyl chloride and hydrogen chloride.

Formula: C₁₁H₁₉NO₂

Purity: Min. 95%

Molecular weight: 197.27 g/mol

Ref: 3D-DEA20178