CAS 103213-32-7

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-L-cysteine

Description:

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-L-cysteine, commonly referred to as Fmoc-Cys(Trt)-OH, is a derivative of the amino acid cysteine, modified for use in peptide synthesis. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely utilized in solid-phase peptide synthesis due to its stability under basic conditions and ease of removal under acidic conditions. The triphenylmethyl (Trt) group serves as a protecting group for the thiol side chain of cysteine, providing stability and preventing undesired reactions during synthesis. The presence of these protective groups allows for selective deprotection at specific stages of peptide assembly. Fmoc-Cys(Trt)-OH is typically a white to off-white solid and is soluble in organic solvents like dimethylformamide (DMF) and dimethyl sulfoxide (DMSO). Its application is primarily in the synthesis of peptides and proteins, particularly those that require the incorporation of cysteine residues, which are crucial for forming disulfide bonds and maintaining structural integrity in proteins.

Formula: C₃₇H₃₁NO₄S

InChI: InChI=1S/C37H31NO4S/c39-35(40)34(38-36(41)42-24-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33)25-43-37(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28/h1-23,33-34H,24-25H2,(H,38,41)(H,39,40)/t34-/m0/s1

InChI key: InChIKey=KLBPUVPNPAJWHZ-UMSFTDKQSA-N

SMILES: C(SC[C@H](NC(OCC1C=2C(C=3C1=CC=CC3)=CC=CC2)=O)C(O)=O)(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6

Synonyms:

• (2R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-tritylsulfanylpropanoic acid
• (2R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-(tritylsulfanyl)propanoate
• (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-(tritylsulfanyl)propanoate
• 2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(tritylthio)propanoic acid
• 3: PN: US20040265921 PAGE: 4 claimed protein
• <span class="text-smallcaps">L</span>-Cysteine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-
• Fmoc-Cys(Trt)-OH
• Fmoc-L-Cys(Trt)-OH
• Fmoc-L-Cysteine(Trityl)
• N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-trityl-<span class="text-smallcaps">L</span>-cysteine
• N-(9-Fluorenyl Methoxy Carbonyl)-S-Trityl-L-Cysteine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-<span class="text-smallcaps">L</span>-cysteine
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-trityl-D-cysteine
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-trityl-L-cysteine
• N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-trityl-L-cysteine
• L-Cysteine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-L-cysteine

CAS: 103213-32-7

Formula: C₃₇H₃₁NO₄S

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 585.72

Ref: 3B-F0652

N-Fmoc-S-trityl-L-cysteine, 95%

CAS: 103213-32-7

It is potentially useful for proteomics studies, and solid phase peptide synthesis techniques. Cysteine is versatile amino acid involved with many biological processes, including the formation of disulfide bonds - a critical component of protein structure. This compound could be useful as an unusual

Formula: C₃₇H₃₁NO₄S

Purity: 95%

Color and Shape: White to pale cream, Powder

Molecular weight: 585.71

Ref: 02-H27363

Fmoc-Cys(Trt)-OH

CAS: 103213-32-7

Standard derivative for Fmoc-SPPS. Educt for obtaining S-alkylated cysteines via thiol-ene reaction.

Formula: C₃₇H₃₁NO₄S

Purity: 99.9421%

Color and Shape: White

Molecular weight: 585.72

Ref: 01-4007272

Fmoc-Cys(Trt)-OH

CAS: 103213-32-7

Formula: C₃₇H₃₁NO₄S

Purity: 97%

Color and Shape: Solid

Molecular weight: 585.7113

Ref: IN-DA0038CZ

Fmoc-Cys(Trt)-OH

CAS: 103213-32-7

Formula: C₃₇H₃₁NO₄S

Purity: ≥ 99.0%

Color and Shape: White to almost white powder

Molecular weight: 585.71

Ref: 7W-GM8515

S-Trityl-L-cysteine, N-FMOC protected

CAS: 103213-32-7

S-Trityl-L-cysteine, N-FMOC protected

Formula: C₃₇H₃₁NO₄S

Purity: 98%

Color and Shape: white solid

Molecular weight: 585.71g/mol

Ref: 54-OR0492

Fmoc-Cys(Trt)-OH

CAS: 103213-32-7

Fmoc-Cys(Trt)-OH, with catalog number T67555 and CAS number 103213-32-7, is a valuable organic compound for life sciences research.

Formula: C₃₇H₃₁NO₄S

Color and Shape: Solid

Molecular weight: 585.72

Ref: TM-T67555

Fmoc-Cys(Trt)-OH

CAS: 103213-32-7

M03395 - Fmoc-Cys(Trt)-OH

Formula: C₃₇H₃₁NO₄S

Purity: 97%

Color and Shape: Solid, Powder or Crystalline Powder

Molecular weight: 585.72

Ref: 10-M03395

S-Trityl-N-Fomc_L-Cysteine

CAS: 103213-32-7

Formula: C₃₇H₃₁NO₄S

Molecular weight: 585.72

Ref: 4Z-C-7721

Fmoc-Cys(Trt)-OH

CAS: 103213-32-7

Fmoc-Cys(Trt)-OH is a cyclic peptide that has potent antitumor activity. It binds to albumin and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. Fmoc-Cys(Trt)-OH has been shown to be effective against cancer cells in vitro and in vivo. Fmoc-Cys(Trt)-OH also binds the plasma glucose, which may be due to its ability to impede insulin release from the pancreas. This compound is synthesized by a stepwise light-induced solid-phase synthesis with trifluoroacetic acid as a solvent.

Formula: C₃₇H₃₁NO₄S

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 585.71 g/mol

Ref: 3D-FF15783

Fmoc-Cys(Trt)-OH

CAS: 103213-32-7

Fmoc-Cys(Trt)-OH is a chemical compound that has been shown to have potent antitumor activity in mice. It is synthesized by the stepwise addition of amino acids to the resin-bound Cys residue in the presence of trifluoroacetic acid and a coupling agent such as EDC. This reaction produces a functional protein with an amide bond. The acetylcholine receptor binding properties of Fmoc-Cys(Trt)-OH are due to its ability to form a disulfide bond with cysteine residues on the receptor.

Formula: C₃₇H₃₁NO₄S

Purity: Min. 98.0 Area-%

Molecular weight: 585.71 g/mol

Ref: 3D-FLC-1718-PI

N-(((9H-Fluoren-9-yl)Methoxy)Carbonyl)-S-Trityl-L-Cysteine-S34

Controlled Product

CAS: 103213-32-7

Formula: C₃₇H₃₁NO₄₃₄S

Color and Shape: Neat

Molecular weight: 587.61

Ref: TR-F403955

S-Trityl-N-Fomc_L-Cysteine-34S

CAS: 103213-32-7

Formula: SC₃₇H₃₁NO₄

Molecular weight: 587.63

Ref: 4Z-C-7722