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CAS 103253-15-2

:

L-655,240

Description:
L-655,240, with the CAS number 103253-15-2, is a chemical compound known for its role as a selective antagonist of the neurokinin-1 (NK1) receptor. This receptor is primarily associated with the action of substance P, a neuropeptide involved in pain perception, stress response, and various neurogenic inflammatory processes. L-655,240 exhibits high affinity for the NK1 receptor, making it a valuable tool in pharmacological research, particularly in studies related to pain management and anxiety disorders. The compound is characterized by its specific binding properties, which allow it to inhibit the action of substance P effectively. Additionally, L-655,240 has been investigated for its potential therapeutic applications in treating conditions such as depression and other mood disorders, where neurokinin signaling may play a significant role. Its chemical structure and properties contribute to its selectivity and efficacy, making it a subject of interest in both academic and clinical research settings.
Formula:C21H21ClFNO2
InChI:InChI=1/C21H21ClFNO2/c1-13-17-10-16(23)8-9-18(17)24(12-14-4-6-15(22)7-5-14)19(13)11-21(2,3)20(25)26/h4-10H,11-12H2,1-3H3,(H,25,26)
SMILES:Cc1c2cc(ccc2n(Cc2ccc(cc2)Cl)c1CC(C)(C)C(=O)O)F
Synonyms:
  • 3-[1-(4-Chlorobenzyl)-5-Fluoro-3-Methyl-Indol-2-Yl]-2,2-Dimethyl Propanoic Acid
  • 1-[(4-Chlorophenyl)Methyl]-5-Fluoro-A,A,3-Trimethyl-1H-Indole-2-Propanoic Acid
  • 1-((4-Chlorophenyl)methyl)-5-fluoro-alpha,alpha-3-trimethyl-(1H)-indole-2-propanoicacid
  • 3-[1-(4-chlorobenzyl)-5-fluoro-3-methyl-1H-indol-2-yl]-2,2-dimethylpropanoic acid
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Found 1 products.
  • 3-[1-[(4-Chlorophenyl)Methyl]-5-Fluoro-3-Methylindol-2-Yl]-2,2-Dimethylpropanoic Acid
    Biosynth
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    3-[1-[(4-Chlorophenyl)Methyl]-5-Fluoro-3-Methylindol-2-Yl]-2,2-Dimethylpropanoic Acid

    Controlled Product
    CAS:
    <p>3-[1-[(4-Chlorophenyl)Methyl]-5-Fluoro-3-Methylindol-2-Yl]-2,2-Dimethylpropanoic Acid is a fluorescent probe that has been shown to be an effective indicator of cytosolic Ca2+ levels in the pancreas. It binds to the acetylcholine receptor and can be used as a marker for the uptake of acetylcholine by nerve cells. 3-[1-[(4-Chlorophenyl)Methyl]-5-Fluoro-3-Methylindol-2-Yl]-2,2-Dimethylpropanoic Acid is also used as an experimental model for protein synthesis and glomerular filtration rate. The compound is a potent antimicrobial agent.</p>
    Formula:C21H21ClFNO2
    Purity:Min. 95%
    Molecular weight:373.85 g/mol

    Ref: 3D-FC101197

    1mg
    303.00€
    5mg
    745.00€
    10mg
    1,065.00€