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CAS 1032759-30-0

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2-Dimethylaminopyrimidine-5-boronic acid pinacol ester

Description:
2-Dimethylaminopyrimidine-5-boronic acid pinacol ester is a chemical compound characterized by its unique structure, which includes a pyrimidine ring substituted with a dimethylamino group and a boronic acid moiety. This compound is typically used in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals, due to its ability to participate in Suzuki coupling reactions, which are essential for forming carbon-carbon bonds. The pinacol ester functionality enhances its stability and solubility, making it more amenable to various synthetic applications. The presence of the boronic acid group allows for the formation of reversible covalent bonds with diols, which is a key feature in the design of molecular sensors and drug delivery systems. Additionally, the dimethylamino group can influence the compound's electronic properties and reactivity, making it a versatile building block in medicinal chemistry. Overall, this compound exemplifies the intersection of boron chemistry and heterocyclic compounds, showcasing its utility in modern synthetic methodologies.
Formula:C12H20BN3O2
Synonyms:
  • 2-(Dimethylamino)pyrimidine-5-boronic acid pinacol ester
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