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CAS 1033201-97-6

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3-Bromo-N-(tert-butyl)-5-methylbenzenesulfonamide

Description:
3-Bromo-N-(tert-butyl)-5-methylbenzenesulfonamide is an organic compound characterized by its sulfonamide functional group, which is known for its applications in medicinal chemistry, particularly as a scaffold in drug development. The presence of the bromine atom at the 3-position of the aromatic ring introduces a halogen that can influence the compound's reactivity and biological activity. The tert-butyl group at the nitrogen atom enhances the lipophilicity of the molecule, potentially improving its membrane permeability. Additionally, the methyl group at the 5-position contributes to the steric bulk and electronic properties of the compound. This compound is likely to exhibit moderate solubility in organic solvents and may have limited solubility in water due to the hydrophobic nature of the tert-butyl group. Its sulfonamide moiety can participate in hydrogen bonding, which may affect its interactions with biological targets. Overall, the structural features of 3-Bromo-N-(tert-butyl)-5-methylbenzenesulfonamide suggest potential utility in various chemical and pharmaceutical applications.
Formula:C11H16BrNO2S
Synonyms:
  • Benzenesulfonamide, 3-bromo-N-(1,1-dimethylethyl)-5-methyl-
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