CAS 103321-49-9
:FMOC-GLY-CL
Description:
FMOC-GLY-CL, also known as 9-fluorenylmethoxycarbonyl glycine chloride, is a chemical compound commonly used in peptide synthesis as a protecting group for amino acids. The FMOC group is a popular choice due to its stability under basic conditions and ease of removal under mild acidic conditions, making it advantageous for sequential peptide synthesis. The presence of the chloride moiety indicates that it can participate in further reactions, such as coupling with other amino acids or nucleophiles. FMOC-GLY-CL is typically a white to off-white solid and is soluble in organic solvents like dichloromethane and dimethylformamide. Its molecular structure includes a fluorenyl group, which contributes to its photophysical properties, and a glycine moiety, which is the simplest amino acid. Safety precautions should be taken when handling this compound, as it may be irritant and requires proper storage conditions to maintain its stability. Overall, FMOC-GLY-CL is a valuable reagent in the field of organic and medicinal chemistry, particularly in the synthesis of peptides and related compounds.
Formula:C17H14ClNO3
Synonyms:- Fmoc Glycyl Chloride
- Chlorocarbonylmethyl-Carbamic Acid 9H-Fluoren-9-Ylmethyl Ester
- NALPHA-9-Fluorenylmethoxycarbonylglycyl chloride
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