Description:HPGDS-inhibitor-1, identified by its CAS number 1033836-12-2, is a chemical compound that functions as an inhibitor of the enzyme hematopoietic prostaglandin D synthase (HPGDS). This enzyme plays a crucial role in the biosynthesis of prostaglandin D2, which is involved in various physiological processes, including inflammation and sleep regulation. The inhibition of HPGDS can have therapeutic implications, particularly in conditions where modulation of prostaglandin levels is beneficial, such as in certain inflammatory diseases or sleep disorders. HPGDS-inhibitor-1 is characterized by its specific binding affinity to the target enzyme, which can be assessed through various biochemical assays. Additionally, its chemical structure may include functional groups that enhance its potency and selectivity. As with many small molecule inhibitors, understanding its pharmacokinetics, bioavailability, and potential side effects is essential for evaluating its suitability for clinical applications. Further research is often required to elucidate its mechanism of action and therapeutic potential in relevant biological contexts.
6-(3-Fluorophenyl)-N-[1-(2,2,2-trifluoroethyl)-4-piperidinyl]-3-pyridinecarboxamide is a prodrug that is converted to its active form by carboxylesterases. It has …
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