CAS 10342-83-3

4'-Bromopropiophenone

Description:

4'-Bromopropiophenone, with the CAS number 10342-83-3, is an organic compound that belongs to the class of ketones. It features a bromine atom substituted at the para position of the phenyl ring relative to the propiophenone moiety. This compound typically appears as a solid, and its molecular structure includes a phenyl group, a propanoyl group, and a bromine substituent, which influences its reactivity and physical properties. 4'-Bromopropiophenone is known for its applications in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. It may exhibit moderate to high lipophilicity due to the presence of the bromine atom and the aromatic ring, which can affect its solubility in various solvents. Additionally, the compound may undergo typical reactions associated with ketones, such as nucleophilic addition and oxidation. Safety precautions should be taken when handling this substance, as it may pose health risks, including irritation or toxicity. Proper storage and disposal methods are essential to mitigate environmental impact.

Formula: C₉H₉BrO

InChI: InChI=1/C9H9BrO/c1-2-9(11)7-3-5-8(10)6-4-7/h3-6H,2H2,1H3

InChI key: InChIKey=UOMOSYFPKGQIKI-UHFFFAOYSA-N

SMILES: C(CC)(=O)C1=CC=C(Br)C=C1

Synonyms:

• 1-(4-Bromophenyl)-1-propanone
• 1-(4-Bromophenyl)Propan-1-One
• 1-(4-Bromophenyl)propanone
• 1-Propanone, 1-(4-bromophenyl)-
• 4-Bromophenyl ethyl ketone
• Ethyl 4-bromophenyl ketone
• NSC 83574
• Propiophenone, 4′-bromo-
• p-Bromopropiophenone
• 4′-Bromopropiophenone
• 4-Bromopropiophenone
• 4?Bromopropiophenone
• AURORA 22532

4'-Bromopropiophenone

CAS: 10342-83-3

Formula: C₉H₉BrO

Purity: >99.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 213.07

Ref: 3B-B1887

4'-Bromopropiophenone

CAS: 10342-83-3

4'-Bromopropiophenone

Formula: C₉H₉BrO

Purity: 98%

Color and Shape: pale yellow solid

Molecular weight: 213.07g/mol

Ref: 54-OR019268

1-(4-Bromophenyl)propan-1-one

CAS: 10342-83-3

1-(4-Bromophenyl)propan-1-one is a sulfonation product of propiophenone. It has been found to have anticancer activity in cervical cancer, and is currently being studied as a potential treatment for cancer. 1-(4-Bromophenyl)propan-1-one can be synthesized by treating propiophenone with hydrochloric acid and sodium hydroxide solution. It can also be synthesized using polyvinyl chloride as the starting material. 1-(4-Bromophenyl)propan-1-one can be isolated from the reaction mixture by adding hydrochloric acid to the reaction mixture, forming a salt that precipitates from solution. This salt is then dissolved in water and neutralized with an alkali such as sodium hydroxide or potassium carbonate, yielding 1-(4-bromophenyl)propan-1-one hydrochloride.

Formula: C₉H₉OBr

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 213.07 g/mol

Ref: 3D-FB142334

4'-Bromopropiophenone

CAS: 10342-83-3

Applications 4'-Bromopropiophenone is an electron-deficient aryl bromide that has the ability to self-polymerize using binary palladium catalyst. 4'-Bromopropiophenone is also used as a reagent in the synthesis of substituted 2-aminothiazoles (e.g. 2-Aminobenzothiazole [A593500]), compounds that are inhibitors of neuronal degeneration in patients with Alzheimer’s disease.
References Bensaid, S., et al.: Tetrahedron Lett., 52, 1383 (2011); Lagoja, I., et al.: Eur. J. Pharm. Sci., 43, 386 (2011); Matsubara, K., et al.: J. Organom. Chem., 691, 3693 (2006)

Formula: C₉H₉BrO

Color and Shape: Neat

Molecular weight: 213.07

Ref: TR-B687245

4'-Bromopropiophenone

CAS: 10342-83-3

Formula: C₉H₉BrO

Purity: 98%

Color and Shape: Solid

Molecular weight: 213.0712

Ref: IN-DA007GP3