CAS 103425-21-4

Scyliorhinin I

Description:

Scyliorhinin I is a bioactive compound derived from the skin of certain species of sharks, particularly the Scyliorhinus genus. It is classified as a peptide and is known for its potential pharmacological properties, including antimicrobial and cytotoxic activities. The structure of Scyliorhinin I features a sequence of amino acids that contribute to its biological functions. This compound has garnered interest in the field of medicinal chemistry due to its unique properties and potential applications in drug development. Research indicates that Scyliorhinin I may interact with various biological targets, making it a subject of study for its therapeutic potential. Additionally, its natural origin raises interest in the exploration of marine-derived compounds for novel pharmaceuticals. As with many peptides, stability and bioavailability are important factors that influence its efficacy and application in clinical settings. Overall, Scyliorhinin I represents a fascinating area of study within the realm of marine biochemistry and pharmacology.

Formula: C₅₉H₈₇N₁₃O₁₃S

InChI: InChI=1/C59H87N13O13S/c1-35(2)29-44(56(82)66-41(51(63)77)25-28-86-4)65-49(74)34-64-53(79)45(32-39-21-23-40(73)24-22-39)69-57(83)46(30-37-15-7-5-8-16-37)71-55(81)43(20-12-14-27-61)68-59(85)48(33-50(75)76)72-58(84)47(31-38-17-9-6-10-18-38)70-54(80)42(19-11-13-26-60)67-52(78)36(3)62/h5-10,15-18,21-24,35-36,41-48,73H,11-14,19-20,25-34,60-62H2,1-4H3,(H2,63,77)(H,64,79)(H,65,74)(H,66,82)(H,67,78)(H,68,85)(H,69,83)(H,70,80)(H,71,81)(H,72,84)(H,75,76)/t36-,41-,42-,43-,44-,45-,46-,47-,48-/m0/s1

SMILES: CC(C)C[C@@H](C(=N[C@@H](CCSC)C(=N)O)O)N=C(CN=C([C@H](Cc1ccc(cc1)O)N=C([C@H](Cc1ccccc1)N=C([C@H](CCCCN)N=C([C@H](CC(=O)O)N=C([C@H](Cc1ccccc1)N=C([C@H](CCCCN)N=C([C@H](C)N)O)O)O)O)O)O)O)O

Synonyms:

• H-Ala-Lys-Phe-Asp-Lys-Phe-Tyr-Gly-Leu-Met-NH2
• L-alanyl-L-lysyl-L-phenylalanyl-L-alpha-aspartyl-L-lysyl-L-phenylalanyl-L-tyrosylglycyl-L-leucyl-L-methioninamide
• SHARK SUBSTANCE P RELATED PEPTIDE
• H-ALA-LYS-PHE-ASP-LYS-PHE-TYR-GLY-LEU-MET-OH
• SCY 1
• AKFDKFYGLM
• Physalemin, 1-de(5-oxo-L-proline)-3-L-lysine-4-L-phenylalanine-5-L-aspartic acid-
• L-Ala-L-Lys-L-Phe-L-Asp-L-Lys-L-Phe-L-Tyr-Gly-L-Leu-L-Met-NH2
• Scyliorhinin I, Scy I
• Scy I: Shark Substance P Related Peptide
• SCYLIORHININ I AMIDE (DOGFISH)
• ALA-LYS-PHE-ASP-LYS-PHE-TYR-GLY-LEU-MET-NH2
• L-Methioninamide, L-alanyl-L-lysyl-L-phenylalanyl-L-α-aspartyl-L-lysyl-L-phenylalanyl-L-tyrosylglycyl-L-leucyl-

Scyliorhinin I

CAS: 103425-21-4

Scyliorhinin I H-Ala-Lys-Phe-Asp-Lys-Phe-Tyr-Gly-Leu-Met-NH2 is a peptide that has been conjugated to an aminopropyl linker. It has shown cardioprotective effects in vitro, which may be due to its ability to inhibit the activity of angiotensin converting enzyme (ACE). Scyliorhinin I H-Ala-Lys-Phe-Asp-Lys-Phe-Tyr-Gly-Leu-Met NH2 also inhibits the production of ACTH and corticosterone in the dogfish. This peptide is not highly potent, but it does have a biphasic response in submandibular gland cells.

Formula: C₅₉H₈₇N₁₃O₁₃S

Purity: Min. 95%

Molecular weight: 1,218.47 g/mol

Ref: 3D-FS108339