CAS 1034301-08-0

3',5'-di-o-p-chlorobenzoyl-2-deoxy-5-azacytosine

Description:

3',5'-di-o-p-chlorobenzoyl-2-deoxy-5-azacytosine is a synthetic nucleoside analog that incorporates modifications to the natural nucleoside structure of cytosine. This compound features a deoxyribose sugar and an azole nitrogen substitution at the 5-position of the cytosine base, which alters its hydrogen bonding properties and potentially its biological activity. The presence of two para-chlorobenzoyl groups at the 3' and 5' positions enhances lipophilicity and may influence the compound's interaction with biological membranes or proteins. The chlorobenzoyl moieties can also provide sites for further chemical modifications or conjugation, making this compound of interest in medicinal chemistry and drug design. Its unique structure may impart specific pharmacological properties, including potential antiviral or anticancer activities, although detailed biological evaluations would be necessary to elucidate its mechanisms of action. As with many synthetic analogs, stability, solubility, and bioavailability are critical factors that would influence its therapeutic potential.

Formula: C₂₂H₁₈Cl₂N₄O₆

Synonyms:

• 3',5'-Bis-O-(4-chlorobenzoyl)-2-deoxy-5-azacytosine
• 3',5'-di-o-p-chlorobenzoyl-2-deoxy-5-azacytosine ISO 9001：2015 REACH
• Decitabine impurity 6/(2R,3S,5R)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-2-(((4-chlorobenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-chlorobenzoate
• Decitabine Intermediate CR
• Decitabine Related Compound B
• Decitabine Impurity 2（Decitabine USP Related Compound B）
• Decitabine USP Related Compound B
• 1,3,5-Triazin-2(1H)-one, 4-amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-β-D-erythro-pentofuranosyl]-
• 3',5'-di-o-p-chlorobenzoyl-2-deoxy-5-azacytosine
• 4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-β-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one
• Decitabine USP RC B
• (2R,3S,5R)-5-(4-Amino-2-oxo-1,3,5-triazin-1(2H)-yl)-2-(((4-chlorobenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-chlorobenzoate
• 4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-beta-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one
• Decitabine Impurity 36
• 1,3,5-Triazin-2(1H)-one,4-amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-b-D-erythro-pentofuranosyl]-
• Decitabine Impurity 2(Decitabine USP RC B)

Decitabine Impurity 36

CAS: 1034301-08-0

Formula: C₂₂H₁₈Cl₂N₄O₆

Color and Shape: White To Off-White Solid

Molecular weight: 505.31

Ref: 4Z-D-7717

3',5'-DI-O-P-CHLOROBENZOYL-2-DEOXY-5-AZACYTOSINE

CAS: 1034301-08-0

Purity: 95.0%

Molecular weight: 323.44

Ref: 10-F514035

β-Decitabine-3',5'-bis(4-chlorobenzoate)

Controlled Product

CAS: 1034301-08-0

Formula: C₂₂H₁₈Cl₂N₄O₆

Color and Shape: Neat

Molecular weight: 505.308

Ref: TR-A601705

3',5'-Di-O-p-chlorobenzoyl-2-deoxy-5-azacytosine

CAS: 1034301-08-0

3',5'-Di-O-p-chlorobenzoyl-2-deoxy-5-azacytosine is a drug product that is an impurity in the synthesis of 5'-azacytosine. The chemical name for 3',5'-Di-O-p-chlorobenzoyl-2-deoxy-5-azacytosine is 3,3'-di(O,O'-dichlorobenzyl)-2,5'-dideoxycytidine. It has a molecular weight of 302.7 g/mol and a melting point of 130°C. This chemical compound has been shown to be metabolized by human liver microsomes to a number of metabolites, including 2-, 3-, and 4-(hydroxymethyl)uracil and 4-(aminomethyl)uracil. 3',5'-Di-O-p-chlorobenzoyl -2 deoxy

Formula: C₂₂H₁₈Cl₂N₄O₆

Purity: Min. 95%

Molecular weight: 505.31 g/mol

Ref: 3D-ID74823

Decitabine USP Related Compound B

CAS: 1034301-08-0

Formula: C₂₂H₁₈Cl₂N₄O₆

Molecular weight: 505.3

Ref: ST-EA-CP-D12007