CAS 10344-94-2

p-Nitrophenyl β-D-glucuronide

Description:

p-Nitrophenyl β-D-glucuronide is a synthetic compound commonly used as a substrate in enzymatic assays, particularly for the detection of β-glucuronidase activity. It is characterized by its structure, which includes a p-nitrophenyl group linked to a glucuronic acid moiety through a β-glycosidic bond. This compound is typically a yellow crystalline solid, and its solubility in water makes it suitable for various biochemical applications. Upon hydrolysis by β-glucuronidase, it releases p-nitrophenol, which can be quantified spectrophotometrically, allowing for the assessment of enzyme activity. The compound is stable under standard laboratory conditions but should be handled with care due to the potential toxicity of p-nitrophenol. Its use in research and clinical diagnostics highlights its importance in understanding metabolic processes and enzyme functions in biological systems.

Formula: C₁₂H₁₃NO₉

InChI: InChI=1/C12H13NO9/c14-7-8(15)10(11(17)18)22-12(9(7)16)21-6-3-1-5(2-4-6)13(19)20/h1-4,7-10,12,14-16H,(H,17,18)/p-1/t7-,8-,9+,10-,12+/m0/s1

InChI key: InChIKey=QSUILVWOWLUOEU-GOVZDWNOSA-N

SMILES: O([C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O)C2=CC=C(N(=O)=O)C=C2

Synonyms:

• (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(4-nitrophenoxy)tetrahydro-2H-pyran-2-carboxylate (non-preferred name)
• 4-Nitrophenol glucuronide
• 4-Nitrophenyl beta-D-glucopyranosiduronic acid
• 4-Nitrophenyl glucuronide
• 4-Nitrophenyl β-<span class="text-smallcaps">D</span>-glucopyranosiduronate
• 4-Nitrophenyl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
• 4-Nitrophenyl β-<span class="text-smallcaps">D</span>-glucosiduronic acid
• 4-Nitrophenyl β-<span class="text-smallcaps">D</span>-glucuronide
• 4-Nitrophenyl-Beta-D-Glucuronide
• 4-Nitrophenylglucuronide
• Glucopyranosiduronic acid, p-nitrophenyl
• Glucopyranosiduronic acid, p-nitrophenyl, β-<span class="text-smallcaps">D</span>-
• p-Nitrophenol glucuronide
• p-Nitrophenol β-<span class="text-smallcaps">D</span>-glucuronide
• p-Nitrophenol β-glucuronide
• p-Nitrophenyl <span class="text-smallcaps">D</span>-glucopyranosiduronic acid
• p-Nitrophenyl beta-D-glucopyranosiduronic acid
• p-Nitrophenyl glucosiduronic acid
• p-Nitrophenyl glucuronic acid
• p-Nitrophenyl glucuronide
• p-Nitrophenyl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
• p-Nitrophenyl β-<span class="text-smallcaps">D</span>-glucosiduronic acid
• p-Nitrophenyl β-<span class="text-smallcaps">D</span>-glucuronide
• p-Nitrophenyl β-glucuronic acid
• p-Nitrophenyl β-glucuronide
• β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, 4-nitrophenyl
• β-D-Glucopyranosiduronic acid, 4-nitrophenyl
• 4-Nitrophenyl β-D-glucopyranosiduronic acid
• p-Nitrophenyl β-D-glucosiduronic acid
• Glucopyranosiduronic acid, p-nitrophenyl, β-D-
• 4-Nitrophenylβ-D-Glucuronide
• P-NITROPHENYL B-D-GLUCURONIDE
• p-Nitrophenyl-β-D-glucuronide
• PNP BETA-D-GLUCURONIDE
• Nitrophenyl-b-D-glucuronide
• P-NITROPHENYL BETA-D-GLUCURONIDE
• (4-NITRO)PHENYL-BETA-D-GLUCORONIDE
• .beta.-D-Glucopyranosiduronic acid, 4-nitrophenyl
• 4-Nitrophenyl-beta-D-glucuronide, 99+%
• NPG
• P-NITROPHENYL BETA-D-GLUCOPYRANOSIDE-URONIC ACID
• 4-NITROPHENYL-BETA-D-GLUCURONIC ACID
• PNP-BETA-D-GLCA
• P-NITROPHENYL BETA-D-GLUCOPYRANOSIDUROINC ACID

4-Nitrophenyl β-D-Glucuronide [Substrate for β-Glucuronidase]

CAS: 10344-94-2

Formula: C₁₂H₁₃NO₉

Purity: >98.0%(HPLC)

Color and Shape: White to Yellow to Orange powder to crystal

Molecular weight: 315.23

Ref: 3B-N0618

4-Nitrophenyl b-D-glucosiduronic acid

CAS: 10344-94-2

Formula: C₁₂H₁₃NO₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 315.2329

Ref: IN-DA003LWA

pNPG-1

CAS: 10344-94-2

pNPG-1

Purity: ≥98%

Molecular weight: 315.23g/mol

Ref: 54-BUP16139

4-Nitrophenyl-β-D-glucuronide

CAS: 10344-94-2

4-Nitrophenyl-β-D-glucuronide

Formula: C₁₂H₁₃NO₉

Purity: >99%

Color and Shape: white solid

Molecular weight: 315.23g/mol

Ref: 54-BIM1203

4-Nitrophenyl b-D-glucuronide

CAS: 10344-94-2

Formula: C₁₂H₁₃NO₉

Purity: ≥ 99.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 315.23

Ref: 7W-GC6761

pNPG-1

CAS: 10344-94-2

pNPG-1(4-Nitrophenyl β-D-glucuronide) is a glucuronide monosaccharide derivative that is a chromogenic substrate for β-glucosidase.

Formula: C₁₂H₁₃NO₉

Purity: 99.88%

Color and Shape: Solid

Molecular weight: 315.23

Ref: TM-T67690

4-Nitrophenyl-beta-D-glucuronic acid

CAS: 10344-94-2

Chromogenic β-glucuronidase substrate yielding a yellow solution upon cleavage. Used to detect E. coli contamination in food and drinking water due to their β-glucuronidase activity.

Formula: C₁₂H₁₃NO₉

Purity: Min. 98.0 Area-%

Molecular weight: 315.24 g/mol

Ref: 3D-N-4450

4-Nitrophenyl b-D-glucosiduronic acid

CAS: 10344-94-2

Formula: C₁₂H₁₃NO₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 315.234

Ref: 10-F240242

p-Nitrophenyl-ß-D-Glucuronide (PNPG (Gus)) extrapure, 99%

CAS: 10344-94-2

Purity: min. 99.0%

Color and Shape: White to off white to pale yellow, Crystalline powder

Ref: SR-92822