CAS 10344-94-2: p-Nitrophenyl β-D-glucuronide

Description: p-Nitrophenyl β-D-glucuronide is a synthetic compound commonly used as a substrate in enzymatic assays, particularly for the detection of β-glucuronidase activity. It is characterized by its structure, which includes a p-nitrophenyl group linked to a glucuronic acid moiety through a β-glycosidic bond. This compound is typically a yellow crystalline solid, and its solubility in water makes it suitable for various biochemical applications. Upon hydrolysis by β-glucuronidase, it releases p-nitrophenol, which can be quantified spectrophotometrically, allowing for the assessment of enzyme activity. The compound is stable under standard laboratory conditions but should be handled with care due to the potential toxicity of p-nitrophenol. Its use in research and clinical diagnostics highlights its importance in understanding metabolic processes and enzyme functions in biological systems.

Formula: C₁₂H₁₃NO₉

InChI: InChI=1S/C12H13NO9/c14-7-8(15)10(11(17)18)22-12(9(7)16)21-6-3-1-5(2-4-6)13(19)20/h1-4,7-10,12,14-16H,(H,17,18)/t7-,8-,9+,10-,12+/m0/s1

InChI key: InChIKey=QSUILVWOWLUOEU-GOVZDWNOSA-N

SMILES: O=C(O)C1OC(OC2=CC=C(C=C2)N(=O)=O)C(O)C(O)C1O

Synonyms:

• (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(4-nitrophenoxy)tetrahydro-2H-pyran-2-carboxylate (non-preferred name)
• 4-Nitrophenol glucuronide
• 4-Nitrophenyl beta-D-glucopyranosiduronic acid
• 4-Nitrophenyl glucuronide
• 4-Nitrophenyl β-<span class="text-smallcaps">D</span>-glucopyranosiduronate
• 4-Nitrophenyl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
• 4-Nitrophenyl β-<span class="text-smallcaps">D</span>-glucosiduronic acid
• 4-Nitrophenyl β-<span class="text-smallcaps">D</span>-glucuronide
• 4-Nitrophenyl-Beta-D-Glucuronide
• 4-Nitrophenylglucuronide
• Glucopyranosiduronic acid, p-nitrophenyl
• Glucopyranosiduronic acid, p-nitrophenyl, β-<span class="text-smallcaps">D</span>-
• p-Nitrophenol glucuronide
• p-Nitrophenol β-<span class="text-smallcaps">D</span>-glucuronide
• p-Nitrophenol β-glucuronide
• p-Nitrophenyl <span class="text-smallcaps">D</span>-glucopyranosiduronic acid
• p-Nitrophenyl beta-D-glucopyranosiduronic acid
• p-Nitrophenyl glucosiduronic acid
• p-Nitrophenyl glucuronic acid
• p-Nitrophenyl glucuronide
• p-Nitrophenyl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
• p-Nitrophenyl β-<span class="text-smallcaps">D</span>-glucosiduronic acid
• p-Nitrophenyl β-<span class="text-smallcaps">D</span>-glucuronide
• p-Nitrophenyl β-glucuronic acid
• p-Nitrophenyl β-glucuronide
• β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, 4-nitrophenyl
• β-D-Glucopyranosiduronic acid, 4-nitrophenyl
• 4-Nitrophenyl β-D-glucopyranosiduronic acid
• p-Nitrophenyl β-D-glucosiduronic acid
• Glucopyranosiduronic acid, p-nitrophenyl, β-D-
• 4-Nitrophenylβ-D-Glucuronide

4-Nitrophenyl β-D-Glucuronide [Substrate for β-Glucuronidase]

CAS: 10344-94-2

• Formula: C₁₂H₁₃NO₉
• Purity: >98.0%(HPLC)
• Color and Shape: White to Yellow to Orange powder to crystal
• Molecular weight: 315.23

4-Nitrophenyl b-D-glucosiduronic acid

CAS: 10344-94-2

• Formula: C₁₂H₁₃NO₉
• Purity: 98%
• Color and Shape: Liquid
• Molecular weight: 315.2329

pNPG-1

CAS: 10344-94-2

• Purity: ≥98%
• Molecular weight: 315.23g/mol

4-Nitrophenyl-β-D-glucuronide

CAS: 10344-94-2

• Formula: C₁₂H₁₃NO₉
• Purity: >99%
• Color and Shape: white solid
• Molecular weight: 315.23g/mol

4-Nitrophenyl b-D-glucuronide

CAS: 10344-94-2

• Formula: C₁₂H₁₃NO₉
• Purity: ≥ 99.0%
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 315.23

4-Nitrophenyl-β-D-glucuronide, 99+%

CAS: 10344-94-2

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₂H₁₂NO₉
• Purity: 99+%
• Color and Shape: White to light yellow, Crystalline powder
• Molecular weight: 314.23

pNPG-1

CAS: 10344-94-2

pNPG-1(4-Nitrophenyl β-D-glucuronide) is a glucuronide monosaccharide derivative that is a chromogenic substrate for β-glucosidase.

• Formula: C₁₂H₁₃NO₉
• Purity: 99.95%
• Color and Shape: Liquid
• Molecular weight: 315.23

4-Nitrophenyl b-D-glucosiduronic acid

CAS: 10344-94-2

• Purity: 95.0%
• Color and Shape: Solid
• Molecular weight: 315.2340087890625

4-Nitrophenyl-β-D-glucuronic acid

CAS: 10344-94-2

Chromogenic β-glucuronidase substrate yielding a yellow solution upon cleavage. Used to detect E. coli contamination …

• Formula: C₁₂H₁₃NO₉
• Purity: Min. 98.0 Area-%
• Molecular weight: 315.24 g/mol

p-Nitrophenyl-ß-D-Glucuronide (PNPG (Gus)) extrapure, 99%

CAS: 10344-94-2

• Purity: min. 99.0%
• Color and Shape: White to off white to pale yellow, Crystalline powder

4-Nitrophenyl b-D-glucuronide

CAS: 10344-94-2

Chromogenic substrate for ?-glucuronidase

• Formula: C₁₂H₁₃NO₉
• Purity: Min. 99 Area-%
• Color and Shape: White Off-White Powder
• Molecular weight: 315.23 g/mol