CAS 1034616-18-6

NMS-P937 (NMS1286937)

Description:

NMS-P937, also known as NMS1286937, is a chemical compound identified by the CAS number 1034616-18-6. It is primarily recognized as a selective inhibitor of the enzyme phosphoinositide 3-kinase (PI3K), which plays a crucial role in various cellular processes, including growth, proliferation, and survival. The compound has garnered attention in the field of cancer research due to its potential therapeutic applications, particularly in targeting specific cancer types that exhibit aberrant PI3K signaling. NMS-P937 is characterized by its unique molecular structure, which facilitates its interaction with the PI3K enzyme, thereby inhibiting its activity. This inhibition can lead to reduced tumor growth and improved outcomes in certain malignancies. Additionally, ongoing studies are exploring its pharmacokinetics, efficacy, and safety profile, which are essential for determining its viability as a treatment option. As research progresses, NMS-P937 may contribute to the development of targeted therapies in oncology, highlighting the importance of understanding its chemical properties and biological effects.

Formula: C₂₄H₂₇F₃N₈O₃

Synonyms:

• NMS-P937 (NMS1286937)
• NMS-P937
• CS-1243
• NMS-1286937
• 4,5-Dihydro-1-(2-hydroxyethyl)-8-[[5-(4-methyl-1-piperazinyl)-2-(trifluoromethoxy)phenyl]amino]-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide
• NMS-P937 (NMS1286937) USP/EP/BP
• 1-(2-hydroxyethyl)-8-[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)anilino]-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide
• NMS-1286937,NMS-P937
• 1H-Pyrazolo[4,3-h]quinazoline-3-carboxamide, 4,5-dihydro-1-(2-hydroxyethyl)-8-[[5-(4-methyl-1-piperazinyl)-2-(trifluoromethoxy)phenyl]amino]-

NMS-P937 (NMS1286937)

CAS: 1034616-18-6

Formula: C₂₄H₂₇F₃N₈O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 532.5182

Ref: IN-DA008TIK

1-(2-Hydroxyethyl)-8-((5-(4-Methylpiperazin-1-Yl)-2-(Trifluoromethoxy)Phenyl)Amino)-4,5-Dihydro-1H-Pyrazolo[4,3-H]Quinazoline-3-Carboxamide

CAS: 1034616-18-6

1-(2-Hydroxyethyl)-8-((5-(4-Methylpiperazin-1-Yl)-2-(Trifluoromethoxy)Phenyl)Amino)-4,5-Dihydro-1H-Pyrazolo[4,3-H]Quinazoline-3-Carboxamide

Purity: 98%

Molecular weight: 532.52g/mol

Ref: 54-PC108449

Onvansertib

CAS: 1034616-18-6

Onvansertib

Purity: ≥95%

Molecular weight: 532.52g/mol

Ref: 54-BUP12847

Onvansertib

CAS: 1034616-18-6

Onvansertib (NMS-1286937) is a PLK1 inhibitor with high selectivity and oral activity. Onvansertib has antitumor activity. Cost-effective and quality-assured.

Formula: C₂₄H₂₇F₃N₈O₃

Purity: 98.3% - 99.88%

Color and Shape: Solid

Molecular weight: 532.52

Ref: TM-T6247

NMS-P937

Controlled Product

CAS: 1034616-18-6

Formula: C₂₄H₂₇F₃N₈O₃

Color and Shape: Neat

Molecular weight: 532.518

Ref: TR-N631750