CAS 1034708-07-0

Ethanone, 2-[(3,4-dichlorophenyl)MethylaMino]-1-[(2R,3R)-3-phenyl-2-(1-pyrrolidinylMethyl)-1-piperidinyl]-, rel-

Description:

Ethanone, 2-[(3,4-dichlorophenyl)methylamino]-1-[(2R,3R)-3-phenyl-2-(1-pyrrolidinylmethyl)-1-piperidinyl]-, also known by its CAS number 1034708-07-0, is a complex organic compound characterized by its multi-functional structure. It features a ketone group (ethanone) and incorporates a dichlorophenyl moiety, which contributes to its potential biological activity. The presence of a piperidine and pyrrolidine ring suggests that this compound may exhibit significant pharmacological properties, possibly interacting with neurotransmitter systems. Its stereochemistry, indicated by the (2R,3R) configuration, may influence its biological interactions and efficacy. The compound's solubility, stability, and reactivity would depend on its specific functional groups and overall molecular structure. As with many synthetic organic compounds, safety and handling precautions are essential, particularly due to the presence of halogenated groups, which can pose environmental and health risks. Further research would be necessary to fully elucidate its properties and potential applications in medicinal chemistry or other fields.

Formula: C₂₅H₃₁Cl₂N₃O

Synonyms:

• Ethanone, 2-[(3,4-dichlorophenyl)MethylaMino]-1-[(2R,3R)-3-phenyl-2-(1-pyrrolidinylMethyl)-1-piperidinyl]-, rel-
• 2-(3,4-dichloro-N-methylanilino)-1-[(2S,3S)-3-phenyl-2-(pyrrolidin-1-ylmethyl)piperidin-1-yl]ethanone

Urotensin-II receptor antagonist-1

CAS: 1034708-07-0

Urotensin-II receptor antagonist-1 (compound 1) is a human Urotensin II receptor antagonist with low oral bioavailability (F=0-3% in rats) and a Ki of 16 nM in HEK293 cells expressing human recombinant UT receptors. It inhibits cytochrome P450 enzymes (IC50=0.75 μM for CYP2D6; 1.4 μM for CYP3A4), suppresses κ opioid receptors (EC50=3.2 μM), and targets cardiac sodium channels (Ki=2.5 μM).

Formula: C₂₅H₃₁Cl₂N₃O

Color and Shape: Solid

Molecular weight: 460.439

Ref: TM-T205347