CAS 103476-89-7

L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-formylbutyl]-, sulfate (2:1)

Description:

L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-formylbutyl]-, sulfate (2:1) is a complex organic compound characterized by its structural components, which include an amino acid derivative (L-leucine) and a sulfate group. This compound features a unique arrangement of functional groups, including amide and acyl functionalities, which contribute to its biological activity and solubility properties. The presence of the sulfate moiety enhances its ionic character, potentially influencing its interaction with biological systems and solubility in aqueous environments. As a derivative of L-leucine, it may exhibit properties related to protein synthesis and metabolism. The compound's stereochemistry, particularly the (1S) configuration, indicates specific spatial arrangements that can affect its biological interactions. Overall, this substance is likely to be of interest in biochemical research, particularly in studies related to peptide synthesis, drug design, and therapeutic applications, although specific biological activities and pharmacological properties would require further investigation.

Formula: C₂₀H₃₈N₆O₄H₂O₄S

InChI: InChI=1S/C20H38N6O4.H2O4S/c1-12(2)9-16(24-14(5)28)19(30)26-17(10-13(3)4)18(29)25-15(11-27)7-6-8-23-20(21)22;1-5(2,3)4/h11-13,15-17H,6-10H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H4,21,22,23);(H2,1,2,3,4)/t15-,16-,17-;/m0./s1

InChI key: InChIKey=IBDASEYBOOUHFZ-FRKSIBALSA-N

SMILES: [C@@H](NC([C@H](CC(C)C)NC(C)=O)=O)(C(N[C@@H](CCCNC(=N)N)C=O)=O)CC(C)C.S(=O)(=O)(O)O

Synonyms:

• (2S)-2-(acetylamino)-N-[(2S)-2-({4-[(diaminomethylidene)amino]-1-formylbutyl}amino)-4-methylpentanoyl]-4-methylpentanamide (non-preferred name)
• 2-(2-Acetamido-4-methylvaleramido)-N-(1-formyl-4-guanidinobutyl)-4-methylvaleramide
• <span class="text-smallcaps">L</smallcap>-Leucinamide, N-acetyl-<smallcap>L</span>-leucyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-formylbutyl]-, sulfate (2:1)
• <span class="text-smallcaps">L</smallcap>-Leucinamide, N-acetyl-<smallcap>L</span>-leucyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, (S)-, sulfate (2:1)
• Acetyl-L-leucyl-L-leucylargininal
• L-Leucinamide, N-acetyl-L-leucyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)-
• Leupeptin Ac-LL
• Leupeptin Hemisulfate From Microbial*Source
• Leupeptin hemisulfate
• N-Acetyl-L-leucyl-L-leucyl-L-argininal
• N-acetyl-L-leucyl-N-{(2S)-5-[(diaminomethylidene)amino]-1-oxopentan-2-yl}-L-leucinamide
• Nk-381
• Valeramide, 2-(2-acetamido-4-methylvaleramido)-N-(1-formyl-4-guanidinobutyl)-4-methyl-
• L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-formylbutyl]-, sulfate (2:1)

L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-formylbutyl]-, sulfate (2:1)

CAS: 103476-89-7

Formula: C₄₀H₇₈N₁₂O₁₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 951.1855

Ref: IN-DA00ILJA

Leupeptin hemisulphate

CAS: 103476-89-7

Leupeptin hemisulphate

Formula: C₂₀H₃₈N₆O₄·H₂SO₄

Purity: >90%

Color and Shape: White to off white Solid-Powder

Molecular weight: 951.18552

Ref: 54-BIMI2183

Leupeptin Hemisulfate

CAS: 103476-89-7

Leupeptin Hemisulfate

Formula: C₂₀H₃₈N₆O₄H₂SO₄

Purity: ≥90%

Molecular weight: 475.59

Ref: 54-BUP13431

Leupeptin hemisulfate

CAS: 103476-89-7

Formula: C₂₀H₃₈N₆O₄·5H₂SO₄

Purity: ≥ 95%

Color and Shape: White to off-white powder

Molecular weight: 475.59

Ref: 7W-GE7125

Leupeptin hemisulfate

CAS: 103476-89-7

(S)-2-Acetamido-N-((S)-1-(((S)-5-guanidino-1-oxopentan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)-4-methylpentanamide hemisulfate

Formula: C₄₀H₇₈N₁₂O₁₂S

Purity: 97%

Molecular weight: 951.19

Ref: IN-DG629844

Leupeptin Hemisulfate

CAS: 103476-89-7

Formula: C₂₀H₃₈N₆O₄H₂O₄S

Molecular weight: 426.56 1/2*98.07

Ref: 4Z-L-175001

Leupeptin Hemisulfate

CAS: 103476-89-7

Leupeptin hemisulfate is a protease inhibitor with cell membrane-permeable, reversible, competitive, and oral activities.

Formula: C₂₀H₃₈N₆O₄H₂SO₄

Purity: 90% - ≥98%

Color and Shape: White Solid

Molecular weight: 475.59

Ref: TM-T6564

Leupeptin hemisulfate anhydrous (vial)

CAS: 103476-89-7

Leupeptin is an ion channel blocker that belongs to the group of protease inhibitors. It blocks the passage of ions across cell membranes by binding to the active site of a variety of enzymes in the membrane. Leupeptin is used as a research tool for studying protein interactions, and can be used for antibody production. Leupeptin is also useful in cell biology studies, because it inhibits the activation of many proteins involved in signal transduction and cell division.

Formula: C₂₀H₃₈N₆O₄

Purity: Min. 95%

Molecular weight: 426.55 g/mol

Ref: 3D-ILP-4041-V

Leupeptin hemisulfate anhydrous

CAS: 103476-89-7

Leupeptin is a protease inhibitor that inhibits the activity of proteases in cells. It has been shown to inhibit transcriptional regulation and apoptosis pathway, as well as possessing anti-inflammatory properties. Leupeptin has been shown to have inhibitory properties against a variety of proteases, including group P2 metalloproteases, cathepsin D, and proteinase 3. This drug has also been shown to prevent neuronal death in experimental models by inhibiting cell lysis. Leupeptin binds to the active site of the enzyme by forming hydrogen bonds with conserved amino acid residues and steric interactions with nearby amino acid residues. The redox potentials of leupeptin are not known, but it is assumed that they are low enough for its antioxidant properties to be effective.

Formula: C₂₀H₃₈N₆O₄H₂SO

Purity: Min. 90 Area-%

Molecular weight: 475.6 g/mol

Ref: 3D-ILP-4041

Leupeptin Hemisulfate

CAS: 103476-89-7

Formula: C₄₀H₇₈N₁₂O₁₂S

Molecular weight: 951.2

Ref: BE-RMCL063001

Leupeptin

CAS: 103476-89-7

A reversible compeptitive protease inhibitor, which was shown to inhibit cathepsins B, H, L, and S, calpain and trypsin. Ac-LLR-CHO inhibits the trypsin-like activity of the proteasome endopeptidase complex. CAS Number (hemisulfate): 103476-89-7.

Formula: C₂₀H₃₈N₆O₄·H₂SO₄

Purity: 97.8380%

Color and Shape: White

Molecular weight: 951.2

Ref: 01-4013467